Excessive abnormal angiogenesis plays a pivotal role in tumor progression and is a
hallmark of solid tumors. This process is driven by an imbalance between pro-and anti …

Sepsis accounts for nearly 700 000 deaths in Europe annually and is caused by an
overwhelming host response to infection resulting in organ failure. The endothelium is an …

BACKGROUND Human pregnancy requires robust hemostasis to prevent hemorrhage
during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification …

Endothelial cells form cell–cell adhesive structures, called adherens and tight junctions,
which maintain tissue integrity, but must be dynamic for leukocyte transmigration during the …

The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …

Tissue engineering strategies to construct vascularized bone grafts potentially revolutionize
the treatment of massive bone loss. The surface topography of the grafts plays critical roles …

Angiogenesis, ie the development and growth of blood vessels, is a major topic of research
as it plays an important role in normal development and in various pathologies. Recent …

It is a big challenge for bone healing under osteoporotic pathological condition with
impaired angiogenesis, osteogenesis and remodeling. In the present study, the effect of Ca …

Endothelial cells lining blood vessels regulate vascular barrier function, which controls the
passage of plasma proteins and circulating cells across the endothelium. In most normal …

Idiopathic pulmonary fibrosis (IPF) is thought to result from aberrant tissue repair processes
in response to chronic or repetitive lung injury. The origin and nature of the injury, as well as …