Induction of mucosal immunity through systemic immunization: Phantom or reality?

F Su, GB Patel, S Hu, W Chen - Human vaccines & …, 2016 - Taylor & Francis
Generation of protective immunity at mucosal surfaces can greatly assist the host defense
against pathogens which either cause disease at the mucosal epithelial barriers or enter the …

Recent advances in developing vaccines against Toxoplasma gondii: an update

NZ Zhang, M Wang, Y Xu, E Petersen… - Expert Review of …, 2015 - Taylor & Francis
Toxoplasma gondii, a significant public health risk, is able to infect almost all warm-blooded
animals including humans, and it results in economic losses in production animals. In the …

Immunological evaluation of a DNA cocktail vaccine with co-delivery of calcium phosphate nanoparticles (CaPNs) against the Toxoplasma gondii RH strain in BALB/c …

MT Rahimi, S Sarvi, M Sharif, S Abediankenari… - Parasitology …, 2017 - Springer
Many recent studies have been conducted to evaluate protective immunity mediated by DNA
vaccines against toxoplasmosis. Cocktail DNA vaccines showed better immune responses …

Vaccination with Toxoplasma lysate antigen or its encapsulated niosomes form immunomodulates adjuvant-induced arthritis through JAK3 downregulation

SS Hassouna, EA Allam, E Sheta, GAM Khodear… - …, 2023 - Springer
Background Inflammatory autoimmune arthritis like that present in rheumatoid arthritis (RA)
is treated by medications with many side effects. This study was a trial to benefit from …

Nano-encapsulated antioxidant: retinoic acid as a natural mucosal adjuvant for intranasal immunization against chronic experimental toxoplasmosis

DE Said, EI Amer, E Sheta, S Makled, FM Arafa… - Tropical Medicine and …, 2023 - mdpi.com
The tight relationship between immunity and retinoid levels provides evidence on the critical
role of retinoic acid (RA) in regulating immune activity, especially the mucosal one. Mucosal …

Vaccination challenges and strategies against long-lived Toxoplasma gondii

FK Loh, S Nathan, SC Chow, CM Fang - Vaccine, 2019 - Elsevier
Since the discovery of Toxoplasma gondii in 1908, it is estimated that one-third of the global
population has been exposed to this ubiquitous intracellular protozoan. The complex life …

Protective efficacy induced by DNA prime and recombinant protein boost vaccination with Toxoplasma gondii GRA14 in mice

AS Pagheh, S Sarvi, S Gholami, H Asgarian-Omran… - Microbial …, 2019 - Elsevier
Toxoplasma gondii, the etiological agent of toxoplasmosis, can cause severe or lethal
damages in both animals and man. So, tends to develop a more effective vaccine to prevent …

Review on the identification and role of Toxoplasma gondii antigenic epitopes

Y Wang, G Wang, J Cai, H Yin - Parasitology research, 2016 - Springer
Toxoplasma gondii is an obligate intracellular protozoan parasite with a broad range of
hosts, and it causes severe toxoplasmasis in both humans and animals. It is well known that …

Evaluation of the immune response in BALB/c mice induced by a novel DNA vaccine expressing GRA14 against Toxoplasma gondii

E Ahmadpour, S Sarvi, MB Hashemi Soteh… - Parasite …, 2017 - Wiley Online Library
Toxoplasma gondii can cause severe and even fatal disease in human beings and animals.
Effective vaccines may contribute to control toxoplasmosis. GRA 14, a novel secreted dense …

Protective effect of a DNA vaccine cocktail encoding ROP13 and GRA14 with Alum nano-adjuvant against Toxoplasma gondii infection in mice

AS Pagheh, A Daryani, P Alizadeh, H Hassannia… - … International Journal of …, 2021 - Elsevier
Toxoplasma gondii is an obligate intracellular protozoan parasite that can cause serious
public health problems. The development of a safe and effective vaccine against T. gondii is …