The hypoxia-inducible factor (HIF) family has three distinct members in most vertebrates. All
three HIFs consist of a unique and oxygen-labile α-subunit and a common and stable β …

Aquaculture is emerging as one of the most viable and promising enterprises for keeping
pace with the surging need for animal protein, providing nutritional and food security to …

Unlike its mammalian counterpart, the adult zebrafish heart is able to fully regenerate after
severe injury. One of the most important events during the regeneration process is …

Aquatic environments exhibit wide temporal and spatial variations in oxygen levels
compared to terrestrial environments. Fish are an excellent model for elucidating the …

Hypoxia is a harmful result of anthropogenic climate change. With the expansion of global
low-oxygen zones (LOZs), many organisms have faced unprecedented challenges affecting …

Endogenous microbiota play essential roles in the host's immune system, physiology,
reproduction and nutrient metabolism. We hypothesized that a continuous administration of …

Habituation represents a fundamental form of learning, yet the underlying molecular genetic
mechanisms are not well defined. Here we report on a genome-wide genetic screen …

Parental influences are a potentially important component of transgenerational transfer of
phenotype in vertebrates. This study examined how chronic hypoxic exposure on adult …

Hypoxia generally refers to a dissolved oxygen (DO) level that is less than 2–3 mg/L. With
ongoing global warming and environment pollution, environmental or geological studies …

The regulation of organ size is essential to human health and has fascinated biologists for
centuries. Key to the growth process is the ability of most organs to integrate organ-extrinsic …