The fluorescent carbocyanine dyes dil and diO have an extensive history of use in cell
biology, but their use as neuronal tracers is relatively recent. We found in 1985 that these …

2.2. Axonal outgrowth 2.3. Formation of neuromuscular junctions 2.4. Developmental death
of motoneurons 2.5. Postnatal elimination of synaptic terminals 3. Methodological …

A prerequisite for many studies of neurons in culture is a means of determining their original
identity. We needed such a technique to study the interactions in vitro between a class of …

In situ hybridization histochemistry and RNA blot analysis were used to study expression of
nerve growth factor receptor (NCF-R) mRNA in rat spinal cord motoneurons. The results …

We present evidence that the cholinergic differentiation factor (CDF), originally purified from
cardiac and skeletal muscle cell-conditioned medium and found to be identical to leukemia …

Neuronal death during the development of the vertebrate nervous system is composed of a
variety of categories, some of which are shared with other developing organ systems, while …

Abstract Treatment of chick embryos in ovo with IGF‐I during the period of normal,
developmentally regulated neuronal death (embryonic days 5–10) resulted in a dose …

Rat sciatic nerves can be transected and their proximal and distal stumps sutured into the
openings of cylindrical silicone chambers. Anatomical regeneration has been demonstrated …

Prolonged denervation results in atrophy of target organs and increased risk of permanent
paralysis. A better understanding of the mechanism responsible for nerve regeneration may …

Treatment of chick embryos in ovo with crude and partially purified extracts from embryonic
hindlimbs (days 8 to 9) during the normal cell death period (days 5 to 10) rescues a …