Causality of genetically determined metabolites on susceptibility to prevalent urological cancers: a two-sample Mendelian randomization study and meta-analysis

X Dai, H Wang, R Zhong, J Li, Y Hou - Frontiers in Genetics, 2024 - frontiersin.org
Background Prevalent urological cancers, including kidney, prostate, bladder, and testicular
cancers, contribute significantly to global cancer incidence and mortality. Metabolomics …

Metabolic Signatures: Pioneering the Frontier of Rectal Cancer Diagnosis and Response to Neoadjuvant Treatment with Biomarkers—A Systematic Review

RA Ciocan, A Ciocan, FV Mihăileanu, CP Ursu… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) is one of the most aggressive, heterogenous, and fatal types of
human cancer for which screening, and more effective therapeutic drugs are urgently …

Curcumol reduces aerobic glycolysis and overcomes chemoresistance by inducing Cdh1-mediated Skp2 ubiquitination

Y Gan, L Zhou, R Wang, Y Zhang, X Li… - The American Journal …, 2023 - World Scientific
Colorectal cancer (CRC) is the third most common cancer worldwide. The main obstacle in
treating advanced CRC is tumor recurrence and metastasis due to chemoresistance. S …

The connection between innervation and metabolic rearrangements in pancreatic cancer through serine

M Dong, L Cao, R Cui, Y Xie - Frontiers in Oncology, 2022 - frontiersin.org
Pancreatic cancer is a kind of aggressive tumor famous for its lethality and intractability, and
pancreatic ductal adenocarcinoma is the most common type. Patients with pancreatic cancer …

Targeting cancer lactate metabolism with synergistic combinations of synthetic catalysts and monocarboxylate transporter inhibitors

HE Bridgewater, EM Bolitho, I Romero-Canelón… - JBIC Journal of …, 2023 - Springer
Synthetic anticancer catalysts offer potential for low-dose therapy and the targeting of
biochemical pathways in novel ways. Chiral organo-osmium complexes, for example, can …

[HTML][HTML] Unveiling Microbiota Profiles in Saliva and Pancreatic Tissues of Patients with Pancreatic Cancer

A Uguz, C Muftuoglu, U Mert, T Gumus, D Ece, M Asadi… - Microorganisms, 2025 - mdpi.com
The pancreas, previously considered a sterile organ, has recently been shown to harbor its
own microbiota that may influence tumor biology and patient outcomes. Despite increasing …

[HTML][HTML] scFASTCORMICS: A Contextualization Algorithm to Reconstruct Metabolic Multi-Cell Population Models from Single-Cell RNAseq Data

MP Pacheco, J Ji, T Prohaska, MM García, T Sauter - Metabolites, 2022 - mdpi.com
Metabolites | Free Full-Text | scFASTCORMICS: A Contextualization Algorithm to
Reconstruct Metabolic Multi-Cell Population Models from Single-Cell RNAseq Data Next …

Future Direction of Cancer Neuroscience

JL Saloman, NN Scheff, BM Davis - Cancer Neuroscience, 2023 - Springer
The chapters in this book summarize the state of the field as we find it in 2023. The
assignment of this last chapter is to look into the future, attempt to guess where cancer …

Construction and Validation of a Prognostic Risk Prediction Model for Lactate Metabolism-Related lncRNA in Endometrial Cancer

F Chang, H Liu, J Wan, Y Gao, Z Wang, L Zhang… - Biochemical …, 2024 - Springer
Endometrial cancer (EC) is a common group of malignant epithelial tumors that mainly occur
in the female endometrium. Lactate is a key regulator of signal pathways in normal and …

[HTML][HTML] Neurogenesis manifestations of solid tumor and tracer imaging studies: a narrative review

Y Huang, B Xiang, A Manyande, H Xiang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
With the emergence of the scientific research field of tumor microenvironment, the idea that
tumor growth and propagation cannot be separated from the tumor microenvironment has …