Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Hydrogen sulfide as a neuromodulator of the vascular tone

SH de la Cruz, GJ Medina-Terol… - European Journal of …, 2023 - Elsevier
Hydrogen sulfide (H 2 S) is a unique signaling molecule that, along with carbon monoxide
and nitric oxide, belongs to the gasotransmitters family. H 2 S is endogenously synthesized …

Central sleep apnea and exposure to ambient hydrogen sulfide emissions from massive strandings of decomposing sargassum in the Caribbean

R Banydeen, MR Lacavalerie, J Florentin… - Science of the Total …, 2024 - Elsevier
Abstract Background Sargassum invasion of Caribbean and American shorelines is a
recurring environmental hazard. Potential health effects of long-term chronic exposure to …

The role of gasotransmitters in neonatal physiology

T Liu, GT Mukosera, AB Blood - Nitric Oxide, 2020 - Elsevier
The gasotransmitters, nitric oxide (NO), hydrogen sulfide (H 2 S), and carbon monoxide
(CO), are endogenously-produced volatile molecules that perform signaling functions …

Hydrogen sulfide production in the medullary respiratory center modulates the neural circuit for respiratory pattern and rhythm generations

M Okazaki, M Matsumoto, T Koganezawa - Scientific Reports, 2023 - nature.com
Abstract Hydrogen sulfide (H2S), which is synthesized in the brain, modulates the neural
network. Recently, the importance of H2S in respiratory central pattern generation has been …

Role of central hydrogen sulfide on ventilatory and cardiovascular responses to hypoxia in spontaneous hypertensive rats

JPJ Sabino, GAA Traslaviña, LGS Branco - Respiratory Physiology & …, 2016 - Elsevier
Central hydrogen sulfide (H 2 S) has been reported to act as a gaseous neuromodulator
involved in the ventilatory and cardiovascular control of normotensive rats, whereas no …

Role of hydrogen sulfide in ventilatory responses to hypercapnia in the medullary raphe of adult rats

JPJ Sabino, LVC Oliveira, RN Soriano… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? There is evidence that H2S plays a
role in the control of breathing: what are its actions on the ventilatory and thermoregulatory …

Increased hypothalamic hydrogen sulphide contributes to endotoxin tolerance by down‐modulating PGE2 production

BM Santos, HDC Francescato, FC Turcato… - Acta …, 2020 - Wiley Online Library
Aim Whereas some patients have important changes in body core temperature (Tb) during
systemic inflammation, others maintain a normal Tb, which is intrinsically associated to …

Lesion of serotonergic afferents to the retrotrapezoid nucleus impairs the tachypneic response to hypercapnia in unanesthetized animals

IP Leirão, DSA Colombari, GSF da Silva, DB Zoccal - Neuroscience, 2021 - Elsevier
Hypercapnia promotes an increase in pulmonary ventilation due to the stimulation of
brainstem chemosensory cells that are connected to the respiratory network. Among these …

Excitatory modulation of the preBötzinger complex inspiratory rhythm generating network by endogenous hydrogen sulfide

GSF da Silva, JPJ Sabino, V Rajani, TS Alvares… - Frontiers in …, 2017 - frontiersin.org
Hydrogen Sulfide (H2S) is one of three gasotransmitters that modulate excitability in the
CNS. Global application of H2S donors or inhibitors of H2S synthesis to the respiratory …