Computational fluid dynamics modeling of liver radioembolization: a review
J Aramburu, R Antón, M Rodriguez-Fraile… - Cardiovascular and …, 2022 - Springer
Abstract Yttrium-90 radioembolization (RE) is a widely used transcatheter intraarterial
therapy for patients with unresectable liver cancer. In the last decade, computer simulations …
therapy for patients with unresectable liver cancer. In the last decade, computer simulations …
Transarterial drug delivery for liver cancer: numerical simulations and experimental validation of particle distribution in patient-specific livers
T Bomberna, GA Koudehi, C Claerebout… - Expert Opinion on …, 2021 - Taylor & Francis
Background: Transarterial therapies are routinely used for the locoregional treatment of
unresectable hepatocellular carcinoma (HCC). However, the impact of clinical parameters …
unresectable hepatocellular carcinoma (HCC). However, the impact of clinical parameters …
Personalized dosimetry for liver cancer Y-90 radioembolization using computational fluid dynamics and Monte Carlo simulation
Abstract Yttrium-90 (Y-90) transarterial radioembolization uses radioactive microspheres
injected into the hepatic artery to irradiate liver tumors internally. One of the major …
injected into the hepatic artery to irradiate liver tumors internally. One of the major …
A proof-of-concept study of the in-vivo validation of a computational fluid dynamics model of personalized radioembolization
R Antón, J Antoñana, J Aramburu, A Ezponda… - Scientific Reports, 2021 - nature.com
Abstract Radioembolization (RE) with yttrium-90 (90Y) microspheres, a transcatheter
intraarterial therapy for patients with liver cancer, can be modeled computationally. The …
intraarterial therapy for patients with liver cancer, can be modeled computationally. The …
Multiscale computational fluid dynamics modeling for personalized liver cancer radioembolization dosimetry
Abstract Yttrium-90 (90Y) radioembolization is a minimally invasive procedure increasingly
used for advanced liver cancer treatment. In this method, radioactive microspheres are …
used for advanced liver cancer treatment. In this method, radioactive microspheres are …
Computational modeling of the liver arterial blood flow for microsphere therapy: effect of boundary conditions
Transarterial embolization is a minimally invasive treatment for advanced liver cancer using
microspheres loaded with a chemotherapeutic drug or radioactive yttrium-90 (90Y) that are …
microspheres loaded with a chemotherapeutic drug or radioactive yttrium-90 (90Y) that are …
Spatiotemporal analysis of particle spread to assess the hybrid particle-flow CFD model of radioembolization of HCC tumors
T Bomberna, S Vermijs, L Bonne… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
Objective: Computational fluid dynamics (CFD) models can potentially aid in pre-operative
planning of transarterial radioactive microparticle injections to treat hepatocellular …
planning of transarterial radioactive microparticle injections to treat hepatocellular …
Virtual lobule models are the key for multiscale biomechanical and pharmacological modeling for the liver
H Ho, E Zhang - Frontiers in physiology, 2020 - frontiersin.org
The liver has a unique dual blood-supply system of hepatic arterial (HA) and portal venous
(PV) vasculatures, which are drained by a hepatic venous (HV) tree (Figure 1A). The blood …
(PV) vasculatures, which are drained by a hepatic venous (HV) tree (Figure 1A). The blood …
The impact of injection distance to bifurcations on yttrium-90 distribution in liver cancer radioembolization
Purpose To model the effect of the injection location on the distribution of yttrium-90 (90 Y)
microspheres in the liver during radioembolization using computational simulation and to …
microspheres in the liver during radioembolization using computational simulation and to …
Development of a scatter correction technique for planar 99mTc-MAA imaging to improve accuracy in lung shunt fraction estimation
N McArdle, S Cournane, J McCavana, J Lucey… - Physica Medica, 2022 - Elsevier
Purpose Prior to 90 Y selective internal radiation therapy (SIRT) treatment, 99m Tc-MAA
scintigraphy imaging is used in the estimation of the lung shunt fraction (LSF). Planar …
scintigraphy imaging is used in the estimation of the lung shunt fraction (LSF). Planar …