Melatonin in type 2 diabetes mellitus and obesity
A Karamitri, R Jockers - Nature Reviews Endocrinology, 2019 - nature.com
Despite considerable advances in the past few years, obesity and type 2 diabetes mellitus
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …
Membrane melatonin receptors activated cell signaling in physiology and disease
G Nikolaev, R Robeva, R Konakchieva - International journal of molecular …, 2021 - mdpi.com
The pineal hormone melatonin has attracted great scientific interest since its discovery in
1958. Despite the enormous number of basic and clinical studies the exact role of melatonin …
1958. Despite the enormous number of basic and clinical studies the exact role of melatonin …
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population
Genetic variants responsible for susceptibility to obesity and its comorbidities among
Hispanic children have not been identified. The VIVA LA FAMILIA Study was designed to …
Hispanic children have not been identified. The VIVA LA FAMILIA Study was designed to …
Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling
Evidence is accumulating regarding the importance of circadian core oscillators, several
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …
Melatonin in aging and disease—multiple consequences of reduced secretion, options and limits of treatment
R Hardeland - Aging and disease, 2011 - pmc.ncbi.nlm.nih.gov
Melatonin is a pleiotropically acting regulator molecule, which influences numerous
physiological functions. Its secretion by the pineal gland progressively declines by age …
physiological functions. Its secretion by the pineal gland progressively declines by age …
Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children
OBJECTIVE To investigate whether associations of common genetic variants recently
identified for fasting glucose or insulin levels in nondiabetic adults are detectable in healthy …
identified for fasting glucose or insulin levels in nondiabetic adults are detectable in healthy …
Sugar-sweetened beverages consumption in relation to changes in body fatness over 6 and 12 years among 9-year-old children: the European Youth Heart Study
Results: Subjects who consumed more than one serve of SSB daily at age 15 years had
larger increases in body mass index (BMI)(β= 0.92, P= 0.046) and waist circumference …
larger increases in body mass index (BMI)(β= 0.92, P= 0.046) and waist circumference …
Zinc Transporter 8 Autoantibodies and Their Association With SLC30A8 and HLA-DQ Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed …
AJ Delli, F Vaziri-Sani, B Lindblad, H Elding-Larsson… - Diabetes, 2012 - Am Diabetes Assoc
We examined whether zinc transporter 8 autoantibodies (ZnT8A; arginine ZnT8-RA,
tryptophan ZnT8-WA, and glutamine ZnT8-QA variants) differed between immigrant and …
tryptophan ZnT8-WA, and glutamine ZnT8-QA variants) differed between immigrant and …
Common Polymorphisms in MTNR1B, G6PC2 and GCK Are Associated with Increased Fasting Plasma Glucose and Impaired Beta-Cell Function in Chinese …
CHT Tam, JSK Ho, Y Wang, HM Lee, VKL Lam… - PloS one, 2010 - journals.plos.org
Background Previous studies identified melatonin receptor 1B (MTNR1B), islet-specific
glucose 6 phosphatase catalytic subunit-related protein (G6PC2), glucokinase (GCK) and …
glucose 6 phosphatase catalytic subunit-related protein (G6PC2), glucokinase (GCK) and …
Minireview: Toward the Establishment of a Link between Melatonin and Glucose Homeostasis: Association of Melatonin MT2 Receptor Variants with Type 2 Diabetes
A Karamitri, N Renault, N Clement… - Molecular …, 2013 - academic.oup.com
The existence of interindividual variations in G protein-coupled receptor sequences has
been recognized early on. Recent advances in large-scale exon sequencing techniques are …
been recognized early on. Recent advances in large-scale exon sequencing techniques are …