Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

Background Cyclophosphamide, in combination with corticosteroids, has been first‐line
treatment for inducing disease remission for proliferative lupus nephritis, reducing death at …

Ethnicity is a biological and a social construct, which includes ancestral genes and cultural,
geographic, and socioeconomic characteristics shared by populations. 1, 2 In contrast, race …

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with diverse
manifestations. Although the approval of new therapies includes only one agent in 50 years …

Systemic lupus erythematosus (SLE) is a ripe area for drug development. There are great
unmet needs, especially for those with lupus nephritis, in which good responses occur only …

Introduction: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with
unpredictable disease course, intermingled with periods of remission and exacerbation …

Introduction: The quest for safer and more effective treatments for systemic lupus
erythematosus (SLE) has led to the development of many new biologic therapies. Abatacept …

Introduction: The approval of belimumab and other advances in the field have narrowed the
window for off-label use of biologicals in systemic lupus erythematosus (SLE). For …

Drug development for the treatment of systemic lupus erythematosus (SLE) has largely
focused on B-cell therapies. A greater understanding of the immunopathogenesis of SLE …

Recently, the use and evaluation of biologics increased in systemic lupus erythematosus
(SLE). However, no international recommendation is available concerning the use of …