Psychotropic drugs can penetrate the blood–brain barrier and regulate the levels of
neurotransmitters and neuromodulators such as γ-aminobutyric acid, glutamate, serotonin …

Drug repurposing is a rapid approach to identify therapeutics for the treatment of emerging
infectious diseases such as COVID-19. To address the urgent need for treatment options, we …

Background Systematic reviewing is a time‐consuming and resource‐intensive process.
Information specialists are maintaining study‐based registers to facilitate efficient conduct of …

Background In the 1940s reserpine, refined from a plant extract that had been used for
centuries, began to be used as a treatment for people with mental disorders and was one of …

Background The efficacy of chlorpromazine, a benchmark antipsychotic, has not been fully
assessed in direct comparison with different individual antipsychotics. Penfluridol is another …

Background: Proline-, glutamic acid-, and leucine-rich protein 1 (PELP1), a co-activator of
estrogen receptors alpha, was confirmed to be directly associated with the oncogenic …

Background Schizophrenia is a chronic, disabling and severe mental disorder,
characterised by disturbance in perception, thought, language, affect and motor behaviour …

Background Chlorpromazine, a widely available and inexpensive antipsychotic drug, is
considered the benchmark treatment for schizophrenia worldwide. Metiapine, a …

Chlorpromazine versus thiothixene for people with schizophrenia - PMC Back to Top Skip to
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Introduction: Continuity of care required for psychotic and schizophrenic patients increases
their life quality significantly. The goal was to assess the specialized care system for …