Gram-negative bacteria characteristically are surrounded by an additional membrane layer,
the outer membrane. Although outer membrane components often play important roles in …

Gram-negative bacteria possess an outer membrane layer which constrains uptake and
secretion of solutes and polypeptides. To overcome this barrier, bacteria have developed …

Autotransporters are a large and diverse superfamily of proteins produced by pathogenic
gram-negative bacteria that are composed of an N-terminal passenger domain, which …

Secretion of proteins across the bacterial outer membrane takes place via a variety of
mechanisms from simple one-component systems to complex multicomponent pathways …

Among the pathways used by gram-negative bacteria for protein secretion, the
autotransporter pathway represents a solution of impressive simplicity. Proteins are …

Autotransporter proteins are a large family of Gram-negative bacterial extracellular proteins.
These proteins have a characteristic arrangement of functional domains, including an N …

Five families of outer membrane porins that function in protein secretion in Gram-negative
bacteria are currently recognized. In this report, these five porin families are analyzed from …

Diarrhea-causing Escherichia coli strains are responsible for numerous cases of
gastrointestinal disease and constitute a serious health problem throughout the world. The …

Two distinct protein secretion pathways, the autotransporter (AT) and the two-partner
secretion (TPS) pathways are characterized by their apparent simplicity. Both are devoted to …

ABSTRACT The Yersinia adhesin YadA is the prototype of a novel class of bacterial
adhesins which form oligomeric lollipop-like structures and are anchored in the outer …