Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

Zinc (II) phthalocyanines as photosensitizers for antitumor photodynamic therapy

LP Roguin, N Chiarante, MCG Vior, J Marino - The international journal of …, 2019 - Elsevier
Photodynamic therapy (PDT) is a highly specific and clinically approved method for cancer
treatment in which a nontoxic drug known as photosensitizer (PS) is administered to a …

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents

M Dichiara, O Prezzavento, A Marrazzo, V Pittala… - European Journal of …, 2017 - Elsevier
In the search of novel strategies for the treatment of cancer, photodynamic therapy (PDT)
has emerged as an effective, safe for repeated use, and non-invasive method. This …

Photophysical, ion-sensing and biological properties of rhodamine-containing transition metal complexes

Q Zhang, KMC Wong - Coordination Chemistry Reviews, 2020 - Elsevier
Rhodamine organic dyes have been known for years and have been applied in biological
studies because of numerous optical advantages, while rhodamine derivatives with spiro …

Mitochondria-Targeted Lipid Nanoparticles Loaded with Rotenone as a New Approach for the Treatment of Oncological Diseases

L Vasileva, G Gaynanova, D Kuznetsova, F Valeeva… - Molecules, 2023 - mdpi.com
This research is based on the concept that mitochondria are a promising target for
anticancer therapy, including thatassociated with the use of oxidative phosphorylation …

Functional aza-boron dipyrromethenes for subcellular imaging and organelle-specific photodynamic therapy

Q Wang, DKP Ng, PC Lo - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
Two hydrophilic aza-boron dipyrromethene (aza-BODIPY) derivatives have first been
designed and synthesised for subcellular imaging. With a triphenylphosphonium or …

Zinc phthalocyanine photochemistry by Raman imaging, fluorescence spectroscopy and femtosecond spectroscopy in normal and cancerous human colon tissues …

B Brozek-Pluska, A Jarota, R Kania, H Abramczyk - Molecules, 2020 - mdpi.com
Photodynamic therapy is a clinically approved alternative method for cancer treatment in
which a combination of nontoxic drugs known as photosensitizers and oxygen is used …

Phthalocyanine-cRGD conjugate: synthesis, photophysical properties and in vitro biological activity for targeting photodynamic therapy

L Luan, W Fang, W Liu, M Tian, Y Ni… - Organic & biomolecular …, 2016 - pubs.rsc.org
An unsymmetrical phthalocyanine conjugated with an RGDyK moiety (6) was synthesized
and characterized. Its photophysical properties, including electronic absorption …

Triphenylphosphonium-substituted phthalocyanine: Design, synthetic strategy, photoproperties and photodynamic activity

M Tarhouni, D Durand, E Önal, D Aggad… - Journal of Porphyrins …, 2018 - World Scientific
In line with current efforts to direct PDT photosensitizers to specific organelles such as
mitochondria, a triphenylphosphonium-tetrasubstituted Zn phthalocyanine was designed …

Recent advances in photosensitizer materials for light‐mediated tumor therapy

M Chen, Q Zhu, Z Zhang, Q Chen… - Chemistry–An Asian …, 2024 - Wiley Online Library
Photodynamic therapy (PDT) as an emerging therapeutic method has drawn many
attentions in the treatment field for cancer. Photosensitizer, which can convert photon energy …