Retinitis pigmentosa (RP) is an important cause of irreversible blindness worldwide and
lacks effective treatment strategies. Although mutations are the primary cause of RP …

Autophagy is a fundamental homeostatic pathway that mediates the degradation and
recycling of intracellular components. It serves as a key quality control mechanism …

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by a
progressive-fibrosing phenotype. IPF has been associated with aberrant HDAC activities …

Inherited retinal diseases, which include retinitis pigmentosa, are a family of genetic
disorders characterized by gradual rod-cone degeneration and vision loss, without effective …

Retinopathy of prematurity (ROP) is one of the leading causes of childhood visual
impairment and blindness. However, there are still very few effective pharmacological …

The search of new therapeutic tools for the treatment of cancer is being a challenge for
medicinal chemists. Due to their role in different pathological conditions, histone …

Simple Summary Uveal melanoma (UM) is the most common adult eye cancer. UM
originates in the iris, ciliary body or choroid (collectively known as the uvea), in the middle …

Visual impairment and blindness are common and seriously affect people's work and quality
of life in the world. Therefore, the effective therapies for eye diseases are of high priority …

Zebrafish are an instrumental system for the generation of photoreceptor degeneration
models, which can be utilized to determine underlying causes of photoreceptor dysfunction …

Programmed cell death (PCD) is a highly regulated process that results in the orderly
destruction of a cell. Many different forms of PCD may be distinguished, including apoptosis …