Oxygen‐free radicals, reactive oxygen species (ROS) or reactive nitrogen species (RNS),
are known by their “double‐sided” nature in biological systems. The beneficial effects of …

Selenium (Se) acts as an essential trace element in the human body due to its unique
biological functions, particularly in the oxidation-reduction system. Although several clinical …

Selenium and selenocompounds have attracted the attention and the efforts of scientists
worldwide due to their promising potential applications in cancer prevention and/or …

Intracellular calcium (Ca2+) concentration ([Ca2+] i) is a key determinant of cell fate and is
implicated in carcinogenesis. Membrane ion channels are structures through which ions …

In recent years, both metal-based complexes and selenium-containing compounds have
been widely explored for their therapeutic properties due to their roles in biological …

Abnormal Ca2+ channel physiology, expression levels, and hypersensitivity to heat have
been implicated in several pain states following treatment with chemotherapeutic agents. As …

Cervical cancer is one of the most common cancers between women and is known as the
third leading cause of female cancer related deaths annually. Its detection in early stages …

Apoptosis, overload Ca 2+ entry and oxidative stress are induced in neurons by hypoxia.
Drug-resistant cancer cells are killed by hypoxic conditions. α-Lipoic acid (ALA) has …

In this study, laryngeal tumor cells were killed through the production of excessive reactive
oxygen species (ROS) and Ca2+ influx by cisplatin (CISP). Nevertheless, a resistance was …

Malignant glioma including glioblastoma (GBM) is the most common group of primary brain
tumors. Despite standard optimized treatment consisting of extensive resection followed by …