Cognitive impairment in schizophrenia involves a broad array of nonsocial and social
cognitive domains. It is a core feature of the illness, and one with substantial implications for …

Psychotic experiences may be understood as altered information processing due to aberrant
neural computations. A prominent example of such neural computations is the computation …

Although circular RNAs (circRNAs) are enriched in the mammalian brain, very little is known
about their potential involvement in brain function and psychiatric disease. Here, we show …

The brain has evolved to produce a diversity of behaviors under stringent computational
resource constraints. Given this limited capacity, how do biological agents balance reward …

Delusions, a core symptom of psychosis, are false beliefs that are rigidly held with strong
conviction despite contradictory evidence. Alterations in inferential processes have long …

Schizophrenia (SZ) has long been associated with a variety of cognitive deficits, including
reduced cognitive flexibility. More recent findings, however, point to tremendous inter …

Schizophrenia is a complex disorder that remains poorly understood, particularly at the
systems level. In this opinion article we argue that the explore/exploit trade-off concept …

The biological basis of the increased risk for psychiatric disorders seen in 15q11. 2 copy
number deletion is unknown. Previous work has shown disturbances in white matter tracts in …

The processing of salient and rewarding stimuli is integral to engaging our attention,
stimulating anticipation for future events, and driving goal-directed behaviors. Widespread …

Schizophrenia is characterized by abnormal perceptions and beliefs, but the computational
mechanisms through which these abnormalities emerge remain unclear. One prominent …