Mechanism of Efferocytosis in Determining Ischaemic Stroke Resolution—Diving into Microglia/Macrophage Functions and Therapeutic Modality

XD Xie, SS Dong, RJ Liu, LL Shi, T Zhu - Molecular Neurobiology, 2024 - Springer
After ischaemic cerebral vascular injury, efferocytosis—a process known as the efficient
clearance of apoptotic cells (ACs) by various phagocytes in both physiological and …

[HTML][HTML] Nano-enhanced nature medicine for ischemic stroke: Opportunities and challenges

J Yang, L Guo, J Liao, H Yi - Biomedical Technology, 2024 - Elsevier
Ischemic stroke (IS), a major cause of death and disability globally, requires innovative
therapeutic approaches due to its complex pathology. Nature medicine (NM) offers …

Holistic Assessment Based On Hepatocyte Mitochondria: Lycopene Repairs Oxidized mtDNA to Alleviate Mitochondrial Stress Induced by Atrazine

TN Yang, YX Wang, PA Jian, XY Ma… - Journal of Agricultural …, 2023 - ACS Publications
Atrazine (ATZ) is a highly persistent herbicide that harms organism health. Lycopene (LYC)
is an antioxidant found in plants and fruits. The aim of this study is to investigate the …

Soluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity

PT Kennedy, EL Saulters, AD Duckworth, YJ Lim… - Molecular Therapy, 2024 - cell.com
CTLA-4 is a crucial immune checkpoint receptor involved in the maintenance of immune
homeostasis, tolerance, and tumor control. Antibodies targeting CTLA-4 have been …

Bone marrow mesenchymal stem cell‐derived dermcidin‐containing migrasomes enhance LC3‐associated phagocytosis of pulmonary macrophages and protect …

T Li, X Su, P Lu, X Kang, M Hu, C Li, S Wang… - Advanced …, 2023 - Wiley Online Library
Pneumonia is one of the leading causes of death in patients with acute ischemic stroke
(AIS). Antibiotics fail to improve prognosis of patients with post‐stroke pneumonia, albeit …

Remodeling and restraining lung tissue damage through the regulation of respiratory immune responses

YJ Pyung, DJ Park, CG Kim, CH Yun - Tissue Engineering and …, 2023 - Springer
Tissue damage caused by various stimuli under certain conditions, such as biological and
environmental cues, can actively induce systemic and/or local immune responses …

Zhilong Huoxue Tongyu Capsule attenuates hemorrhagic transformation through the let-7f/TLR4 signaling pathway

L Geng, LZ Zheng, YF Kang, CL Pan, T Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Hemorrhagic transformation after acute ischemic stroke is
a life-threatening disease that currently has no effective chemotherapy. Zhilong Huoxue …

Bone marrow-derived mesenchymal stem cell ameliorates post-stroke enterobacterial translocation through liver-gut axis

X Su, T Li, Y Wang, L Wei, B Jian, X Kang… - Stroke and Vascular …, 2024 - svn.bmj.com
Background Enterobacterial translocation is a leading contributor to fatal infection among
patients with acute ischaemic stroke (AIS). Accumulative evidence suggests that …

Dynamic change of neutrophil‐to‐lymphocyte ratio and its predictive value of prognosis in acute ischemic stroke

K Qian, J Hu, C Wang, C Xu, Y Chen, Q Feng… - Brain and …, 2024 - Wiley Online Library
Objective The present research aimed to explore the dynamic change of the neutrophil‐to‐
lymphocyte ratio (NLR) and its relationship with functional outcome following an acute …

Beclin-1: a therapeutic target at the intersection of autophagy, immunotherapy, and cancer treatment

Z Cao, K Tian, Y Ran, H Zhou, L Zhou, Y Ding… - Frontiers in …, 2024 - frontiersin.org
The significant identification of Beclin-1's function in regulating autophagy flow signified a
significant progression in our understanding of cellular operations. Beclin-1 acts as a …