Developmental neurotoxicity of succeeding generations of insecticides

Y Abreu-Villaça, ED Levin - Environment international, 2017 - Elsevier
Insecticides are by design toxic. They must be toxic to effectively kill target species of insects.
Unfortunately, they also have off-target toxic effects that can harm other species, including …

Residential exposure to pesticides as risk factor for childhood and young adult brain tumors: A systematic review and meta-analysis

G Van Maele-Fabry, L Gamet-Payrastre… - Environment international, 2017 - Elsevier
Background Accumulating evidence suggests a positive association between exposure to
non-agricultural pesticides and childhood brain tumors (CBT). Objective (1) To conduct a …

Role of microRNAs in neurodegeneration induced by environmental neurotoxicants and aging

T Singh, S Yadav - Ageing research reviews, 2020 - Elsevier
The progressive loss of neuronal structure and functions resulting in the death of neurons is
considered as neurodegeneration. Environmental toxicants induced degeneration of …

Developmental exposure to pesticides alters motor activity and coordination in rats: sex differences and underlying mechanisms

B Gómez-Giménez, V Felipo, A Cabrera-Pastor… - Neurotoxicity …, 2018 - Springer
It has been proposed that developmental exposure to pesticides contributes to increasing
prevalence of neurodevelopmental disorders in children, such as attention deficit with …

Cypermethrin stimulates GSK3β-dependent Aβ and p-tau proteins and cognitive loss in young rats: reduced HB-EGF signaling and downstream neuroinflammation as …

SK Maurya, J Mishra, S Abbas… - Molecular neurobiology, 2016 - Springer
Pesticide exposure is recognized as a risk factor for Alzheimer's disease (AD). We
investigated early signs of AD-like pathology upon exposure to a pyrethroid pesticide …

Severe pulmonary toxicity associated with inhalation of pyrethroid-based domestic insecticides (Bop/Sapolio): a case series and literature review

ADM Vorselaars, PM van den Berg… - Current opinion in …, 2021 - journals.lww.com
We present three cases of severe pulmonary toxicity after inhalation of pyrethroid-based
insecticides demanding hospitalization and oxygen therapy. One of these cases died …

Histologic features of postnatal development of immune system organs in the Sprague-Dawley rat

GA Parker, CA Picut, C Swanson… - Toxicologic …, 2015 - journals.sagepub.com
The immune system of the rat undergoes substantial functional and morphological
development during the postnatal period. Some aspects of this development are genetically …

Early-life exposure to commercial formulation containing deltamethrin and cypermethrin insecticides impacts redox system and induces unexpected regional effects in …

F Mekircha, D Fedeli, C Nasuti, H Kecies… - Antioxidants, 2023 - mdpi.com
Several studies have shown that the oxidative impact of pesticides is most prevalent in rural
environments where they are intensively used. At different levels, pyrethroids are reported to …

Endosulfan and cypermethrin pesticide mixture induces synergistic or antagonistic effects on developmental exposed rats depending on the analyzed behavioral or …

B Gomez-Gimenez, M Llansola… - ACS chemical …, 2018 - ACS Publications
Exposure to pesticides has been associated with neurodevelopmental toxicity. Usually
people are exposed to mixtures of pesticides. However, most studies analyze the effects of …

Transactivation of P53 by cypermethrin induced miR-200 and apoptosis in neuronal cells

A Pandey, A Jauhari, T Singh, P Singh… - Toxicology …, 2015 - academic.oup.com
Cypermethrin, a pyrethroid pesticide, has been shown to induce neurotoxicity in adult
mammals. However, studies are also needed to explore its toxicity in developing brains and …