The liver is a unique parenchymal organ with a regenerative capacity allowing it to restore
up to 70% of its volume. Although knowledge of this phenomenon dates back to Greek …

Cancers of the urinary tract, as well as those of the female and male reproductive systems,
account for a large percentage of malignancies worldwide. Mortality is frequently affected by …

Abstract Glycogen synthase kinase 3 (GSK3) is a monomeric serine-threonine kinase
discovered in 1980 in a rat skeletal muscle. It has been involved in various cellular …

Purpose Signaling by cancer stem cells (CSCs) is known to occur at least in part through
conserved developmental pathways. Here, the role of one of these pathways, ie, the …

Borderline ovarian tumors (BOTs) are a type of low malignant potential tumor that is typically
associated with better outcomes than ovarian cancer. Indeed, its 10-year survival rate is as …

Simple Summary Chemotherapy is the mainstay of cancer treatment; however, its use is
limited due to the emergence of chemotherapeutic drug resistance in cancers. An essential …

Cumulative studies have provided controversial evidence for the prognostic values of bone
morphogenetic protein 5 (BMP5) in different types of cancers such as colon, breast, lung …

Simple Summary The majority of melanomas show hyperactivation of the MAPK signaling
pathway, most often through mutations in BRAF and NRAS. Despite significant progress in …

Background: This study aimed to explore the effect of GANT61 on ovarian cancer (OC)
chemosensitivity. Materials & methods: OC cells (Caov-3 and SKOV-3) were treated by …

Abstract Background The Sonic Hedgehog (SHH) signaling pathway plays an important role
in various types of human cancers including ovarian cancer; however, its function and …