NGseqBasic-a single-command UNIX tool for ATAC-seq, DNaseI-seq, Cut-and-Run, and ChIP-seq data mapping, high-resolution visualisation, and quality control

J Telenius, WIGWAM Consortium, JR Hughes - bioRxiv, 2018 - biorxiv.org
With decreasing cost of next-generation sequencing (NGS), we are observing a rapid rise in
the volume of 'big data'in academic research, healthcare and drug discovery sectors. The …

DOT1L complex suppresses transcription from enhancer elements and ectopic RNAi in Caenorhabditis elegans

R Esse, ES Gushchanskaia, A Lord, A Grishok - RNA, 2019 - rnajournal.cshlp.org
Methylation of histone H3 on lysine 79 (H3K79) by DOT1L is associated with actively
transcribed genes. Earlier, we described that DOT-1.1, the Caenorhabditis elegans homolog …

DOT1L suppresses nuclear RNAi originating from enhancer elements in Caenorhabditis elegans

R Esse, E Gushchanskaia, A Lord, A Grishok - bioRxiv, 2018 - biorxiv.org
Methylation of histone H3 lysine 79 (H3K79) by DOT1L is associated with actively
transcribed genes. We have previously demonstrated that DOT-1.1, the Caenorhabditis …