Diabetes is a highly prevalent disease associated with considerable cardiovascular end
organ damage and mortality. Despite significant changes to the management of acute …

Background No study evaluated the incidence of intra-stent restenosis (ISR)-related events
in patients with type 2 diabetes (T2DM) and acute myocardial infarction (AMI) treated or not …

Oxidative stress and endothelial dysfunction have been shown to play crucial roles in the
pathophysiology of COVID-19 (coronavirus disease 2019). On these grounds, we sought to …

Myeloid-derived growth factor (MYDGF) is a paracrine protein produced by bone marrow-
derived monocytes and macrophages. Current research shows that it has protective effects …

Introduction: Increasingly, SGLT2 inhibitors save patients with heart failure and
comorbidities such as type-2 diabetes mellitus (T2DM) and chronic kidney disease (CKD); …

Diabetes mellitus, an epidemic with a rapidly increasing number of patients, always leads to
delayed wound healing associated with consistent pro-inflammatory M1 polarization …

Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are widely used in cardiology and are
effective in treating acute coronary syndrome (ACS). Their effects on unstable plaque in …

Background Frailty is a multidimensional condition typical of elders. Frail older adults have a
high risk of functional decline, hospitalization, and mortality. Hypertension is one of the most …

Restenosis after angioplasty is caused usually by neointima formation characterized by
aberrant vascular smooth muscle cell (VSMC) dedifferentiation. Myeloid-derived growth …

Background Diabetes exacerbates neointima formation after vascular procedures,
manifested by accelerated proliferation and migration of vascular smooth muscle cells …