Pancreatic cancer: a review of current treatment and novel therapies

HM Kolbeinsson, S Chandana, GP Wright… - Journal of Investigative …, 2023 - Taylor & Francis
Pancreatic cancer is one of the leading causes for cancer-related deaths in the United
States. Majority of patients present with unresectable or metastatic disease. For those that …

Meta-analysis comparing upfront surgery with neoadjuvant treatment in patients with resectable or borderline resectable pancreatic cancer

E Versteijne, JA Vogel, MG Besselink… - Journal of British …, 2018 - academic.oup.com
Background Studies comparing upfront surgery with neoadjuvant treatment in pancreatic
cancer may report only patients who underwent resection and so survival will be skewed …

Pancreatic adenocarcinoma, version 2.2017, NCCN clinical practice guidelines in oncology

MA Tempero, MP Malafa, M Al-Hawary… - Journal of the National …, 2017 - jnccn.org
Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-
quality multiphase imaging can help to preoperatively distinguish between patients eligible …

Pancreatic ductal adenocarcinoma: current and evolving therapies

A Adamska, A Domenichini, M Falasca - International journal of molecular …, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is
the fourth leading cause of cancer-related deaths in the world. Due to the broad …

Neoadjuvant FOLFIRINOX in patients with borderline resectable pancreatic cancer: a systematic review and patient-level meta-analysis

QP Janssen, S Buettner, M Suker… - JNCI: Journal of the …, 2019 - academic.oup.com
Background FOLFIRINOX is a standard treatment for metastatic pancreatic cancer patients.
The effectiveness of neoadjuvant FOLFIRINOX in patients with borderline resectable …

Neoadjuvant treatment in pancreatic cancer

A Oba, F Ho, QR Bao, MH Al-Musawi… - Frontiers in …, 2020 - frontiersin.org
Thanks to the development of modern chemotherapeutic regimens, survival after surgery for
pancreatic ductal adenocarcinoma (PDAC) has improved and pancreatologists worldwide …

Pancreatic cancer: from state-of-the-art treatments to promising novel therapies

I Garrido-Laguna, M Hidalgo - Nature reviews Clinical oncology, 2015 - nature.com
Pancreatic cancer is expected to be the second deadliest malignancy in the USA by 2020.
The survival rates for patients with other gastrointestinal malignancies have increased …

[HTML][HTML] Addressing the challenges of pancreatic cancer: future directions for improving outcomes

M Hidalgo, S Cascinu, J Kleeff, R Labianca, JM Löhr… - Pancreatology, 2015 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC), which accounts for more than 90% of all
pancreatic tumours, is a devastating malignancy with an extremely poor prognosis, as …

Defining and predicting early recurrence in 957 patients with resected pancreatic ductal adenocarcinoma

VP Groot, G Gemenetzis, AB Blair… - Annals of …, 2019 - journals.lww.com
Objectives: To establish an evidence-based cut-off to differentiate between early and late
recurrence and to compare clinicopathologic risk factors between the two groups. Summary …

Recent progress in pancreatic cancer

CL Wolfgang, JM Herman, DA Laheru… - CA: a cancer journal …, 2013 - Wiley Online Library
Answer questions and earn CME/CNE Pancreatic cancer is currently one of the deadliest of
the solid malignancies. However, surgery to resect neoplasms of the pancreas is safer and …