Papilledema: a review of etiology, pathophysiology, diagnosis, and management

JS Xie, L Donaldson, E Margolin - Survey of Ophthalmology, 2022 - Elsevier
Papilledema is optic nerve head edema secondary to raised intracranial pressure (ICP). It is
distinct from other causes of optic disk edema in that visual function is usually normal in the …

Idiopathic intracranial hypertension: a step change in understanding the disease mechanisms

A Yiangou, SP Mollan, AJ Sinclair - Nature Reviews Neurology, 2023 - nature.com
The understanding of idiopathic intracranial hypertension (IIH) has evolved over the past few
years. Previously, IIH was considered a disease exclusively affecting the neuro-ophthalmic …

Effectiveness of bariatric surgery vs community weight management intervention for the treatment of idiopathic intracranial hypertension: a randomized clinical trial

SP Mollan, JL Mitchell, RS Ottridge, M Aguiar… - JAMA …, 2021 - jamanetwork.com
Importance Idiopathic intracranial hypertension (IIH) causes headaches, vision loss, and
reduced quality of life. Sustained weight loss among patients with IIH is necessary to modify …

The expanding burden of idiopathic intracranial hypertension

SP Mollan, M Aguiar, F Evison, E Frew, AJ Sinclair - Eye, 2019 - nature.com
Objective To quantify the hospital burden and health economic impact of idiopathic
intracranial hypertension. Methods Hospital Episode Statistics (HES) national data was …

The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial

JL Mitchell, HS Lyons, JK Walker, A Yiangou, O Grech… - Brain, 2023 - academic.oup.com
Therapeutics to reduce intracranial pressure are an unmet need. Preclinical data have
demonstrated a novel strategy to lower intracranial pressure using glucagon-like peptide-1 …

European headache federation guideline on idiopathic intracranial hypertension

J Hoffmann, SP Mollan, K Paemeleire, C Lampl… - The journal of headache …, 2018 - Springer
Abstract Background Idiopathic Intracranial Hypertension (IIH) is characterized by an
elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely …

The idiopathic intracranial hypertension prospective cohort study: evaluation of prognostic factors and outcomes

M Thaller, V Homer, Y Hyder, A Yiangou… - Journal of …, 2023 - Springer
Background There are limited longitudinal data evaluating outcomes in idiopathic
intracranial hypertension (IIH). We aimed to evaluate the long-term outcomes in a real-world …

Idiopathic intracranial hypertension: pathophysiology, diagnosis and management

MTM Wang, MT Bhatti, HV Danesh-Meyer - Journal of Clinical …, 2022 - Elsevier
Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure,
manifested by papilledema and radiological findings, in the absence of an identifiable …

Using optical coherence tomography as a surrogate of measurements of intracranial pressure in idiopathic intracranial hypertension

V Vijay, SP Mollan, JL Mitchell, E Bilton… - JAMA …, 2020 - jamanetwork.com
Importance There is an unmet need for noninvasive biomarkers of intracranial pressure
(ICP), which manifests as papilledema that can be quantified by optical coherence …

[HTML][HTML] Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension

CSJ Westgate, HF Botfield, Z Alimajstorovic… - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Idiopathic intracranial hypertension (IIH) is a condition predominantly
affecting obese women of reproductive age. Recent evidence suggests that IIH is a disease …