Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …

The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

Abstract γδ T cells play uniquely important roles in stress surveillance and immunity for
infections and carcinogenesis. Human γδ T cells recognize and kill transformed cells …

Clinical responses to checkpoint inhibitors used for cancer immunotherapy seemingly
require the presence of αβT cells that recognize tumour neoantigens, and are therefore …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Summary Vγ9Vδ2 T cells respond in a TCR-dependent fashion to both microbial and host-
derived pyrophosphate compounds (phosphoantigens, or P-Ag). Butyrophilin-3A1 …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

γδ T cells, αβ T cells, and B cells are present together in all but the most primitive
vertebrates, suggesting that each population contributes to host immune competence …

T lymphocytes comprise cells expressing either an αβ or a γδ TCR. The riddle how αβ TCRs
are triggered by specific peptides presented in the context of MHC was elucidated some …

The unique features of gamma-delta (γδ) T cells, related to their antigen recognition
capacity, their tissue tropism, and their cytotoxic function, make these cells ideal candidates …