Osteoporosis is a condition of increased bone fragility associated with fractures. Apart from
primary genetic osteoporotic conditions, secondary osteoporosis in children is being …

Osteoporosis is a major public health problem with serious long-term complications. In
children, the definition of osteoporosis is not only based on densitometric criteria but also …

Bisphosphonates prevent bone loss in glucocorticoid (GC)-treated boys with Duchenne
muscular dystrophy (DMD) and are recommended as standard of care. Targeting receptor …

Background Continuous use of glucocorticoids (GCs) has become the primary cause of
secondary osteoporosis. Bisphosphonate drugs were given priority over denosumab and …

Context Zoledronate appears to reduce fracture rates in children with cerebral palsy (CP),
but no previous randomized, controlled trial has been performed to compare the effect of …

Purpose Zoledronic acid can inhibit the activity of osteoclasts, and thus, may slow or inhibit
bone loss. The purpose of this study was to systematically evaluate the efficacy and safety of …

Patients with Duchenne muscular dystrophy (DMD) have a high fracture burden due to
progressive myopathy and steroid-induced osteoporosis. This study in males with DMD …

By definition, children constitute a vulnerable population, especially when they are
chronically ill and/or disabled. A characteristic of chronically ill and disabled children is that …

Cantú syndrome (CS) is caused by the gain of function mutations in the ABCC9 and KCNJ8
genes encoding, respectively, for the sulfonylureas receptor type 2 (SUR2) and the inwardly …

Glucocorticoids (GCs) are essential and effective medications commonly prescribed to
patients with autoimmune disorders and inflammatory diseases. However, they often …