The implications of adopting protective hemodynamics are profound for both clinical practice
and research. Clinically, this approach can reduce iatrogenic harm and improve long-term …

Background Intravenous antihypertensivedrugs are commonly used in acute care settings,
yet their impact on cerebral blood flow (CBF) remains uncertain. Methods A systematic …

Perioperative and critically ill patients share similarities in hemodynamic management,
particularly in the use of inotropes and vasopressors, as well as in the need for continuous …

Background Cardiogenic shock (CS) presents a medical challenge with limited treatment
options. Positive end-expiratory pressure (PEEP) during mechanical ventilation has been …

Background Noradrenaline is a standard treatment for hypotension in acute care. The
precise effects of noradrenaline on cerebral blood flow in health and disease remain …

Psilocin is a well-studied controlled substance with potential psychotherapeutic applications.
However, research gaps remain regarding its metabolism. Our objective was to elucidate a …

Within the next century, the proportion of people aged 65 years or older is expected to grow
dramatically1, necessitating extensive research into diseases common among older adults …

Methods and Results: This doctoral dissertation consisted of four papers, referred to by
roman numerals. 4D flow MRI and computed tomography angiography (CTA) were applied …