The increasing challenge of multiple chronic diseases (multimorbidity) requires more
evidence-based knowledge and effective practice. In order to better understand the existing …

Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …

The important role of GH in the control of mammalian longevity was first deduced from
extended longevity of mice with genetic GH deficiency (GHD) or GH resistance. Mice with …

Prenatal effects on telomere length are increasingly recognized as a potential contributor to
the developmental origin of health and adult disease. While it is becoming clear that …

Curcumin, a low molecular weight, lipophilic, major yellow natural polyphenolic, and the
most well-known plant-derived compound, is extracted from the rhizomes of the turmeric …

The development of high-throughput omics technologies represents an unmissable
opportunity for evidence-based prevention of adverse effects on human health. However …

Metabolic changes in pregnant women begin in the first weeks after conception under the
influence of placental hormones that affect the metabolism of all nutrients. An increased …

Cardiovascular ageing and the atherosclerotic process begin very early in life, most likely in
utero. They progress over decades of exposure to suboptimal or abnormal metabolic and …

Aging is spontaneous and inevitable process in all living beings. It is a complex natural
phenomenon that manifests as a gradual decline of physiological functions and …

Oxidative stress has been implicated in the pathophysiology of numerous terrestrial disease
processes and associated with morbidity following spaceflight. Furthermore, oxidative stress …