Complement‐driven hemolytic uremic syndrome
J Leon, MB LeStang, R Sberro‐Soussan… - American Journal of …, 2023 - Wiley Online Library
Overactivation of the complement alternative pathway drives the pathogenesis of primary
atypical hemolytic uremic syndrome (aHUS). Genetically‐determined or acquired …
atypical hemolytic uremic syndrome (aHUS). Genetically‐determined or acquired …
Diagnosis and Treatment for Shiga Toxin-Producing Escherichia coli Associated Hemolytic Uremic Syndrome
Shiga toxin-producing Escherichia coli (STEC)-associated hemolytic uremic syndrome
(STEC-HUS) is a clinical syndrome involving hemolytic anemia (with fragmented red blood …
(STEC-HUS) is a clinical syndrome involving hemolytic anemia (with fragmented red blood …
Eculizumab in Pediatric Kidney Disorders: A Review
Eculizumab is a humanized monoclonal antibody targeting the C5 (complement 5) member
of complement proteins and inhibiting its cleavage to C5a and C5b. Eculizumab has been …
of complement proteins and inhibiting its cleavage to C5a and C5b. Eculizumab has been …