Microglia are the only immune cells that permanently reside in the central nervous system
(CNS) alongside neurons and other types of glial cells. The past decade has witnessed a …

Microglia were recently shown to play unexpected roles in normal brain development and
adult physiology. This has begun to dramatically change our view of these resident …

Despite increasing evidence supporting the neuroinflammatory theory of depression, little is
known about cerebral macrophages in individuals suffering from major depression. In the …

Background Microglia can adopt different morphologies, ranging from a highly ramified to an
amoeboid-like phenotype. Although morphological properties of microglia have been …

Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons
and inflammatory responses. Whereas microglia are very competent phagocytes under …

Phagocytosis is essential to maintain tissue homeostasis in a large number of inflammatory
and autoimmune diseases, but its role in the diseased brain is poorly explored. Recent …

Suicide is one of the most disastrous outcomes for psychiatric disorders. Recent advances in
biological psychiatry have suggested a positive relationship between some specific brain …

Microglia represent the immune system of the brain. Their role is central in two phenomena,
neuroinflammation and oxidative stress, which are at the roots of different pathologies …

Microglia can shift into different complex morphologies depending on the microenvironment
of the central nervous system (CNS). The distinct morphologies correlate with specific …

Microglia constitute the major immune cells that permanently reside in the central nervous
system (CNS) alongside neurons and other glial cells. These resident immune cells are …