H Shi, Y Koronyo, A Rentsendorj, DT Fuchs… - Frontiers in …, 2021 - frontiersin.org
The retina has been increasingly investigated as a site of Alzheimer's disease (AD) manifestation for over a decade. Early reports documented degeneration of retinal ganglion …
Alzheimer's disease (AD) is the leading cause of dementia that has remained a major medical, sociocultural and economical challenge globally. Previously developed treatments …
T Smit, NAC Deshayes, DR Borchelt, W Kamphuis… - Glia, 2021 - Wiley Online Library
Astrocytes regulate synaptic communication and are essential for proper brain functioning. In Alzheimer's disease (AD) astrocytes become reactive, which is characterized by an …
A Kasindi, DT Fuchs, Y Koronyo, A Rentsendorj… - Cells, 2022 - mdpi.com
Novel, neuroprotective uses of Copaxone (generic name: glatiramer acetate—GA) are being examined, primarily in neurological conditions involving cognitive decline. GA is a well …
L Wang, X Mao - International journal of molecular sciences, 2021 - mdpi.com
Amyloid-β (Aβ) accumulations have been identified in the retina for neurodegeneration- associated disorders like Alzheimer's disease (AD), glaucoma, and age-related macular …
Alzheimer's disease (AD) is a neurodegenerative condition that primarily affects brain tissue. Because the retina and brain share the same embryonic origin, visual deficits have been …
H Shi, Y Koronyo, DT Fuchs, J Sheyn… - Acta Neuropathologica …, 2020 - Springer
Extensive effort has been made studying retinal pathology in Alzheimer's disease (AD) to improve early noninvasive diagnosis and treatment. Particularly relevant are vascular …
L Wang, X Wei - Frontiers in Immunology, 2021 - frontiersin.org
Glaucoma as the leading neurodegenerative disease leads to blindness in 3.6 million people aged 50 years and older worldwide. For many decades, glaucoma therapy has …
J Alber, F Bouwman, J den Haan… - Alzheimer's & …, 2024 - Wiley Online Library
There is emerging evidence that amyloid beta protein (Aβ) and tau‐related lesions in the retina are associated with Alzheimer's disease (AD). Aβ and hyperphosphorylated (p)‐tau …