The role of tissue engineering in articular cartilage repair and regeneration

L Zhang, J Hu, KA Athanasiou - Critical Reviews™ in …, 2009 - dl.begellhouse.com
Articular cartilage repair and regeneration continue to be largely intractable because of the
poor regenerative properties of this tissue. The field of articular cartilage tissue engineering …

[HTML][HTML] A critical review on polymer-based bio-engineered materials for scaffold development

HY Cheung, KT Lau, TP Lu, D Hui - Composites Part B: Engineering, 2007 - Elsevier
Since the last decade, tissue engineering has shown a sensational promise in providing
more viable alternatives to surgical procedures for harvested tissues, implants and …

Mechanical properties of natural cartilage and tissue-engineered constructs

CJ Little, NK Bawolin, X Chen - Tissue Engineering Part B: Reviews, 2011 - liebertpub.com
There has been much research over the past two decades with the aim of engineering
cartilage constructs for repairing or restoring damaged cartilage. To engineer healthy …

[PDF][PDF] A combination of shear and dynamic compression leads to mechanically induced chondrogenesis of human mesenchymal stem cells

O Schätti, S Grad, J Goldhahn, G Salzmann, Z Li… - Eur Cell …, 2011 - researchgate.net
There is great interest in how bone marrow derived stem cells make fate decisions.
Numerous studies have investigated the role of individual growth factors on mesenchymal …

Cartilage tissue engineering: its potential and uses

CK Kuo, WJ Li, RL Mauck, RS Tuan - Current opinion in …, 2006 - journals.lww.com
Cell selection, scaffold design and biological stimulation remain the challenges of function
tissue engineering. Successful regeneration or replacement of damaged or diseased …

Mechanical load modulates chondrogenesis of human mesenchymal stem cells through the TGF‐β pathway

Z Li, L Kupcsik, SJ Yao, M Alini… - Journal of cellular and …, 2010 - Wiley Online Library
This study investigated the effect of mechanical load on human mesenchymal stem cell
(hMSC) differentiation under different exogenous transforming growth factor‐β1 (TGF‐β1) …

Long-term mechanical loading is required for the formation of 3D bioprinted functional osteocyte bone organoids

J Zhang, J Griesbach, M Ganeyev, AK Zehnder… - …, 2022 - iopscience.iop.org
Mechanical loading has been shown to influence various osteogenic responses of bone-
derived cells and bone formation in vivo. However, the influence of mechanical stimulation …

Physical stimulation of chondrogenic cells in vitro: a review

S Grad, D Eglin, M Alini… - Clinical Orthopaedics and …, 2011 - journals.lww.com
Background Mechanical stimuli are of crucial importance for the development and
maintenance of articular cartilage. For conditioning of cartilaginous tissues, various …

[图书][B] Articular cartilage

KA Athanasiou, EM Darling, JC Hu, GD DuRaine… - 2017 - taylorfrancis.com
This book covers the latest research and advancements related to articular cartilage in
biology, development, pathology, clinical applications and tissue engineering. The authors …

Chondrogenesis of human bone marrow mesenchymal stem cells in fibrin–polyurethane composites is modulated by frequency and amplitude of dynamic …

Z Li, SJ Yao, M Alini, MJ Stoddart - Tissue Engineering Part A, 2010 - liebertpub.com
In this study, human bone marrow mesenchymal stem cell (hMSC)–seeded fibrin–
polyurethane composite scaffolds were subjected to various mechanical load protocols to …