Heroin on trial: systematic review and meta-analysis of randomised trials of diamorphine-prescribing as treatment for refractory heroin addiction

J Strang, T Groshkova, A Uchtenhagen… - The British Journal of …, 2015 - cambridge.org
BackgroundSupervised injectable heroin (SIH) treatment has emerged over the past 15
years as an intensive treatment for entrenched heroin users who have not responded to …

Opioid use disorder and treatment: challenges and opportunities

KA Hoffman, J Ponce Terashima, D McCarty - BMC health services …, 2019 - Springer
Background Addiction health service researchers have focused efforts on opioid use
disorder (OUD) and strategies to address the emerging public health threats associated with …

Effect of Risk Mitigation Guidance opioid and stimulant dispensations on mortality and acute care visits during dual public health emergencies: retrospective cohort …

A Slaunwhite, JE Min, H Palis, K Urbanoski, B Pauly… - bmj, 2024 - bmj.com
Objective To determine the effect of opioid and stimulant Risk Mitigation Guidance (RMG)
dispensations on mortality and acute care visits during the dual public health emergencies …

Hydromorphone compared with diacetylmorphine for long-term opioid dependence: a randomized clinical trial

E Oviedo-Joekes, D Guh, S Brissette… - JAMA …, 2016 - jamanetwork.com
Importance Diacetylmorphine hydrochloride (the active ingredient in heroin), delivered
under supervision, is effective for the treatment of severe opioid use disorder. However …

Losing the uphill battle? Emergent harm reduction interventions and barriers during the opioid overdose crisis in Canada

C Strike, TM Watson - International Journal of Drug Policy, 2019 - Elsevier
Canada continues to experience an escalating opioid overdose crisis that has claimed more
than 8000 lives in the country since 2016. The presence of the synthetic opioid fentanyl and …

Evaluation of risk mitigation measures for people with substance use disorders to address the dual public health crises of COVID-19 and overdose in British Columbia …

B Nosyk, A Slaunwhite, K Urbanoski, N Hongdilokkul… - BMJ open, 2021 - bmjopen.bmj.com
Introduction The COVID-19 pandemic was preceded by an ongoing overdose crisis and
linked to escalating drug overdose deaths in British Columbia (BC). At the outset of these …

HIV prevention in clinical care settings: 2014 recommendations of the International Antiviral Society–USA Panel

JM Marrazzo, C Del Rio, DR Holtgrave, MS Cohen… - Jama, 2014 - jamanetwork.com
Importance Emerging data warrant the integration of biomedical and behavioral
recommendations for human immunodeficiency virus (HIV) prevention in clinical care …

Factors associated with 60-day adherence to “safer supply” opioids prescribed under British Columbia's interim clinical guidance for health care providers to support …

M Selfridge, K Card, T Kandler, E Flanagan… - International Journal of …, 2022 - Elsevier
Abstract Aims In March 2020, British Columbia issued Risk Mitigation Guidance (RMG) to
support prescribing of pharmaceutical alternatives to illicit drugs, in order to reduce risk for …

A call for evidence-based medical treatment of opioid dependence in the United States and Canada

B Nosyk, MD Anglin, S Brissette, T Kerr, DC Marsh… - Health …, 2013 - healthaffairs.org
Despite decades of experience treating heroin or prescription opioid dependence with
methadone or buprenorphine—two forms of opioid substitution therapy—gaps remain …

Economic evaluations of opioid use disorder interventions

SM Murphy, D Polsky - Pharmacoeconomics, 2016 - Springer
Background The economic costs associated with opioid misuse are immense. Effective
interventions for opioid use disorders are available; however, given the scarce resources …