The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …

The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

Background The long non-coding RNA PVT1 (lncRNA PVT1) has been reported to act as an
oncogenic regulator of several cancers. However, its expression and function in gallbladder …

Pancreatic cancer is one of the most common causes of cancer death in the world due to the
lack of early symptoms, metastasis occurrence and chemoresistance. Therefore, early …

Abstract Development of resistance to chemotherapeutic drugs is a major challenge in the
care of patients with pancreatic ductal adenocarcinoma (PDAC). Acquired resistance to …

Background Myeloid-derived suppressor cells (MDSCs) participate in tumor-elicited
immunosuppression by dramatically blocking T-cell-induced antitumor responses, thereby …

Background Defective autophagy is thought to contribute to the pathogenesis of many
diseases, including cancer. Human plasmacytoma variant translocation 1 (PVT1) is an …

The plasmacytoma variant translocation 1 gene (PVT1) is an oncogenic lncRNA with
regulative effect on chemosensitivity in cervical cancer. However, the underlying …

The plasmacytoma variant translocation 1 gene (PVT1) is an lncRNA that has been
designated as an oncogene due to its contribution to the phenotype of multiple cancers …

The role of long noncoding RNAs (lncRNAs) in the epithelial‐mesenchymal transition (EMT)
in pancreatic ductal adenocarcinoma (PDAC) is unclear. Some lncRNAs can be transferred …