Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life

KA Walker, J Chen, L Shi, Y Yang, M Fornage… - Science translational …, 2023 - science.org
A diverse set of biological processes have been implicated in the pathophysiology of
Alzheimer's disease (AD) and related dementias. However, there is limited understanding of …

Global gene expression profiling and transcription factor network analysis of cognitive aging in monozygotic twins

A Mohammadnejad, W Li, JB Lund, S Li… - Frontiers in …, 2021 - frontiersin.org
Cognitive aging is one of the major problems worldwide, especially as people get older. This
study aimed to perform global gene expression profiling of cognitive function to identify …

Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community

CC Soo, JT Brandenburg, A Nebel, S Tollman… - Communications …, 2023 - nature.com
Cognitive function is an indicator for global physical and mental health, and cognitive
impairment has been associated with poorer life outcomes and earlier mortality. A standard …

Differential lncRNA expression profiling of cognitive function in middle and old aged monozygotic twins using generalized association analysis

A Mohammadnejad, J Baumbach, W Li, J Lund… - Journal of Psychiatric …, 2021 - Elsevier
Cognitive impairment is the most prominent symptom in neurodegenerative disorders
affecting quality of life and mortality. However, despite years of research, the molecular …

[HTML][HTML] Identifying genetic variants regulating MGMT gene expression-A study in monozygotic Danish twins

A Mohammadnejad, M Soerensen, J Mengel-From… - Genomics, 2023 - Elsevier
Identifying genetic factors affecting the regulation of the O-6-Methylguanine-DNA
Methyltransferase (MGMT) gene and estimating the genetic contribution of the MGMT gene …

Structural variants in linkage disequilibrium with GWAS-significant SNPs

H Liang, JC Sedillo, SJ Schrodi, A Ikeda - Heliyon, 2024 - cell.com
With the recent expansion of structural variant identification in the human genome,
understanding the role of these impactful variants in disease architecture is critically …