Fundamental photophysics of isomorphic and expanded fluorescent nucleoside analogues
Fluorescent nucleoside analogues (FNAs) are structurally diverse mimics of the natural
essentially non-fluorescent nucleosides which have found numerous applications in probing …
essentially non-fluorescent nucleosides which have found numerous applications in probing …
Probing of nucleic acid structures, dynamics, and interactions with environment-sensitive fluorescent labels
Fluorescence labeling and probing are fundamental techniques for nucleic acid analysis
and quantification. However, new fluorescent probes and approaches are urgently needed …
and quantification. However, new fluorescent probes and approaches are urgently needed …
Human Telomeric DNA Forms Parallel-Stranded Intramolecular G-Quadruplex in K+ Solution under Molecular Crowding Condition
The G-rich strand of human telomeric DNA can fold into a four-stranded structure called G-
quadruplex and inhibit telomerase activity that is expressed in 85− 90% tumor cells. For this …
quadruplex and inhibit telomerase activity that is expressed in 85− 90% tumor cells. For this …
2-aminopurine as a fluorescent probe of DNA conformation and the DNA–enzyme interface
Nearly 50 years since its potential as a fluorescent base analogue was first recognized, 2-
aminopurine (2AP) continues to be the most widely used fluorescent probe of DNA structure …
aminopurine (2AP) continues to be the most widely used fluorescent probe of DNA structure …
[图书][B] DNA and RNA modification enzymes: structure, mechanism, function and evolution
H Grosjean - 2009 - taylorfrancis.com
This volume is a timely and comprehensive description of the many facets of DNA and RNA
modification-editing processes and to some extent repair mechanisms. Each chapter offers …
modification-editing processes and to some extent repair mechanisms. Each chapter offers …
Fluorescent DNA-based enzyme sensors
N Dai, ET Kool - Chemical Society Reviews, 2011 - pubs.rsc.org
Fluorescent sensors that make use of DNA structures have become widely useful in
monitoring enzymatic activities. Early studies focused primarily on enzymes that naturally …
monitoring enzymatic activities. Early studies focused primarily on enzymes that naturally …
Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue
P Sandin, K Börjesson, H Li, J Mårtensson… - Nucleic acids …, 2008 - academic.oup.com
This article presents the first evidence that the DNA base analogue 1, 3-diaza-2-
oxophenoxazine, tC O, is highly fluorescent, both as free nucleoside and incorporated in an …
oxophenoxazine, tC O, is highly fluorescent, both as free nucleoside and incorporated in an …
Switching on the fluorescence of 2-aminopurine by site-selective microhydration
Aminopurine (2AP) is a fluorescent isomer of adenine and has a fluorescence lifetime of~ 11
ns in water. It is widely used in biochemical settings as a site-specific fluorescent probe of …
ns in water. It is widely used in biochemical settings as a site-specific fluorescent probe of …
Conquering 2-aminopurine's deficiencies: highly emissive isomorphic guanosine surrogate faithfully monitors guanosine conformation and dynamics in DNA
The archetypical fluorescent nucleoside analog, 2-aminopurine (2Ap), has been used in
countless assays, though it suffers from very low quantum yield, especially when included in …
countless assays, though it suffers from very low quantum yield, especially when included in …
Environmentally sensitive fluorescent nucleoside analogues as probes for nucleic acid–protein interactions: molecular design and biosensing applications
D Dziuba - Methods and Applications in Fluorescence, 2022 - iopscience.iop.org
Fluorescent nucleoside analogues (FNAs) are indispensable in studying the interactions of
nucleic acids with nucleic acid-binding proteins. By replacing one of the poorly emissive …
nucleic acids with nucleic acid-binding proteins. By replacing one of the poorly emissive …