[HTML][HTML] Sequence-Based Protein Design: A Review of Using Statistical Models to Characterize Coevolutionary Traits for Developing Hybrid Proteins as Genetic …
Statistical analyses of homologous protein sequences can identify amino acid residue
positions that co-evolve to generate family members with different properties. Based on the …
positions that co-evolve to generate family members with different properties. Based on the …
Protein stability is determined by single-site bias rather than pairwise covariance
M Sternke, KW Tripp, D Barrick - bioRxiv, 2025 - biorxiv.org
The biases revealed in protein sequence alignments have been shown to provide
information related to protein structure, stability, and function. For example, sequence biases …
information related to protein structure, stability, and function. For example, sequence biases …