Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …

Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …

Cuproptosis, caused by excessively high copper concentrations, is urgently exploited as a
potential cancer therapeutic. However, the mechanisms underlying the initiation …

Copper homeostasis is strictly regulated by protein transporters and chaperones, to allow its
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …

Recent studies have established a strong link between copper and cancer biology, as
copper is necessary for cancer growth and metastasis. Beyond the conventional concept of …

Abstract Coronavirus disease-2019 (COVID-19) pandemic continues to threaten patients,
societies, and economic and healthcare systems around the world. Like many other …

Copper is one of the most abundant basic transition metals in the human body. It takes part
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …

Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …

Copper is an essential microelement that plays an important role in a wide variety of
biological processes. Copper concentration has to be finely regulated, as any imbalance in …