Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission

S Karthikeyan, JI Levy, P De Hoff, G Humphrey… - Nature, 2022 - nature.com
As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical
for public health interventions. Inferring lineage prevalence by clinical testing is infeasible at …

Systematic detection of co-infection and intra-host recombination in more than 2 million global SARS-CoV-2 samples

OA Pipek, A Medgyes-Horváth, J Stéger… - Nature …, 2024 - nature.com
Systematic monitoring of SARS-CoV-2 co-infections between different lineages and
assessing the risk of intra-host recombinant emergence are crucial for forecasting viral …

Online dashboards for SARS-CoV-2 wastewater-based epidemiology

D Focosi, PG Spezia, F Maggi - Future Microbiology, 2024 - Taylor & Francis
Aim: Wastewater-based epidemiology (WBE) is increasingly used to monitor pandemics. In
this manuscript, we review methods and limitations of WBE, as well as their online …

[HTML][HTML] Identification of a rare SARS-CoV-2 XL hybrid variant in wastewater and the subsequent discovery of two infected individuals in Nevada

V Vo, A Harrington, S Afzal, K Papp, CL Chang… - Science of The Total …, 2023 - Elsevier
The identification of novel SARS-CoV-2 variants can predict new patterns of COVID-19
community transmission and lead to the deployment of public health resources. However …

SARS-CoV-2 wastewater genomic surveillance: approaches, challenges, and opportunities

V Munteanu, M Saldana, D Ciorba, V Bostan… - arXiv preprint arXiv …, 2023 - arxiv.org
During the SARS-CoV-2 pandemic, wastewater-based genomic surveillance (WWGS)
emerged as an efficient viral surveillance tool that takes into account asymptomatic cases …

Wastewater early warning system for SARS-CoV-2 outbreaks and variants in a Coruña, Spain

N Trigo-Tasende, JA Vallejo, S Rumbo-Feal… - … Science and Pollution …, 2023 - Springer
Wastewater-based epidemiology has been widely used as a cost-effective method for
tracking the COVID-19 pandemic at the community level. Here we describe COVIDBENS, a …

Performance of methods for SARS-CoV-2 variant detection and abundance estimation within mixed population samples

T Kayikcioglu, J Amirzadegan, H Rand, B Tesfaldet… - PeerJ, 2023 - peerj.com
Background The accurate identification of SARS-CoV-2 (SC2) variants and estimation of
their abundance in mixed population samples (eg, air or wastewater) is imperative for …

Systematic SARS-CoV-2 S-gene sequencing in wastewater samples enables early lineage detection and uncovers rare mutations in Portugal

AC Reis, D Pinto, S Monteiro, R Santos… - Science of the Total …, 2024 - Elsevier
As the COVID-19 pandemic reached its peak, many countries implemented genomic
surveillance systems to track the evolution and transmission of SARS-CoV-2. Transition from …

Genomic surveillance reveals early detection and transition of delta to omicron lineages of SARS-CoV-2 variants in wastewater treatment plants of Pune, India

V Rajput, R Pramanik, V Malik, R Yadav… - … Science and Pollution …, 2023 - Springer
The COVID-19 pandemic has emphasized the urgency for rapid public health surveillance
methods to detect and monitor the transmission of infectious diseases. The wastewater …

Tracking SARS-CoV-2 variants of concern in wastewater: an assessment of nine computational tools using simulated genomic data

SG Sutcliffe, SA Kraemer, I Ellmen… - Microbial …, 2024 - microbiologyresearch.org
Wastewater-based surveillance (WBS) is an important epidemiological and public health
tool for tracking pathogens across the scale of a building, neighbourhood, city, or region …