Therapeutic agents that are able to prevent or attenuate inflammation and ischemia-induced
injury of neural and retinal cells could be used for the treatment of neural and retinal …

Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly
understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse …

Macrophage polarization toward the M1 phenotype and its subsequent inflammatory
response have been implicated in the progression of diabetic complications. Despite …

Biologically produced reactive oxygen species (ROS) are important signaling molecules in
the human body. Despite their importance under normal conditions, abnormal …

Radiotherapy (RT)-induced tumoricidal immunity is severely limited when tumors are well-
established. Here, we report that depleting SIRPα on intratumoral macrophages augments …

Aim To evaluate the ability of ladarixin (LDX, 400 mg twice‐daily for three cycles of 14 days
on/14 days off), an inhibitor of the CXCR1/2 chemokine receptors, to maintain C‐peptide …

The severe form of coronavirus disease 19 (COVID-19) is characterized by cytokine storm
syndrome (CSS) and disseminated intravascular coagulation (DIC). Diabetes, obesity, and …

Diabetes mellitus is a complex metabolic disease associated with reduced synaptic
plasticity, atrophy of the hippocampus, and cognitive decline. Cognitive impairment results …

Scope Syringaresinol (SYR) is a phenolic compound, which could be found in various
cereals and medicinal plants. It exerts both anti‐inflammatory and antioxidant …

The pathogenesis of diabetic nephropathy is not completely understood, and the effects of
existing treatments are not satisfactory. Various public platforms already contain extensive …