Cancer immunotherapies that harness the body's immune system to combat tumors have
received extensive attention and become mainstream strategies for treating cancer. Despite …

Abstract Interleukin 12 (IL-12) seemed to represent the ideal candidate for tumor
immunotherapy, due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T …

Accumulating evidence indicates that the innate and adaptive immune systems make a
crucial contribution to the antitumour effects of conventional chemotherapy-based and …

Purpose: The unique mechanism of tumor destruction by photodynamic therapy (PDT),
resulting from apoptotic and necrotic killing of tumor cells accompanied by local …

Background: Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-
type immune response against cancer, a condition where cells in a particular part of the …

Accumulating evidence suggests that despite the potency of cytotoxic anticancer agents,
and the great specificity that can be achieved with immunotherapy, neither of these two …

Epigenetic regulation allows heritably modulating gene expression profiles without
modifying the primary sequence of gDNA. Under physiologic conditions, epigenetic patterns …

Photodynamic therapy (PDT) uses the combination of non-toxic photosensitizers and
harmless light to generate reactive oxygen species that destroy tumors by a combination of …

For several decades, we have known that epigenetic regulation is disrupted in cancer.
Recently, an increasing body of data suggests epigenetics might be an intersection of …

Photodynamic therapy (PDT) is a clinically approved therapeutic modality used for the
management of several types of tumors as well as non-malignant diseases. Most of the …