Reproductive risk factors and breast cancer subtypes: a review of the literature

KN Anderson, RB Schwab, ME Martinez - Breast cancer research and …, 2014 - Springer
Aside from age, sex, and family history, risk of developing breast cancer is largely linked to
reproductive factors, which characterize exposure to sex hormones. Given that, molecular …

Hereditary breast cancer: the era of new susceptibility genes

P Apostolou, F Fostira - BioMed research international, 2013 - Wiley Online Library
Breast cancer is the most common malignancy among females. 5%–10% of breast cancer
cases are hereditary and are caused by pathogenic mutations in the considered reference …

The SLC4 family of bicarbonate (HCO3-) transporters

MF Romero, AP Chen, MD Parker, WF Boron - Molecular aspects of …, 2013 - Elsevier
The SLC4 family consists of 10 genes (SLC4A1–5; SLC4A7–11). All encode integral
membrane proteins with very similar hydropathy plots—consistent with 10–14 …

The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transporters

MD Parker, WF Boron - Physiological reviews, 2013 - journals.physiology.org
The mammalian Slc4 (Solute carrier 4) family of transporters is a functionally diverse group
of 10 multi-spanning membrane proteins that includes three Cl-HCO3 exchangers (AE1–3) …

Gene–environment interaction and risk of breast cancer

A Rudolph, J Chang-Claude, MK Schmidt - British journal of cancer, 2016 - nature.com
Hereditary, genetic factors as well as lifestyle and environmental factors, for example, parity
and body mass index, predict breast cancer development. Gene–environment interaction …

[HTML][HTML] Association between common risk factors and molecular subtypes in breast cancer patients

FP Turkoz, M Solak, I Petekkaya, O Keskin, N Kertmen… - The breast, 2013 - Elsevier
BACKGROUND: Breast cancer is the most commonly diagnosed cancer in women
worldwide and characterized its by molecular and clinical heterogeneity. Gene expression …

Polygenic scores in cancer

X Yang, S Kar, AC Antoniou, PDP Pharoah - Nature reviews Cancer, 2023 - nature.com
Since the publication of the first genome-wide association study for cancer in 2007,
thousands of common alleles that are associated with the risk of cancer have been …

Cohort profile: the Melbourne collaborative cohort study (health 2020)

RL Milne, AS Fletcher, RJ MacInnis… - International journal …, 2017 - academic.oup.com
The Melbourne Collaborative Cohort Study (MCCS), also known as Health 2020, was
planned in the late 1980s and established in the early 1990s as an omnibus cohort to …

Evidence of gene–environment interactions between common breast cancer susceptibility loci and established environmental risk factors

S Nickels, T Truong, R Hein, K Stevens, K Buck… - PLoS …, 2013 - journals.plos.org
Various common genetic susceptibility loci have been identified for breast cancer; however,
it is unclear how they combine with lifestyle/environmental risk factors to influence risk. We …

Characterization of gene–environment interactions for colorectal cancer susceptibility loci

CM Hutter, J Chang-Claude, ML Slattery… - Cancer research, 2012 - AACR
Genome-wide association studies (GWAS) have identified more than a dozen loci
associated with colorectal cancer (CRC) risk. Here, we examined potential effect …