Bioactive milk peptides: An updated comprehensive overview and database

SDH Nielsen, N Liang, H Rathish, BJ Kim… - Critical Reviews in …, 2024 - Taylor & Francis
Partial digestion of milk proteins leads to the formation of numerous bioactive peptides.
Previously, our research team thoroughly examined the decades of existing literature on …

[HTML][HTML] Yogurt and cardiometabolic diseases: a critical review of potential mechanisms

MA Fernandez, S Panahi, N Daniel, A Tremblay… - Advances in …, 2017 - Elsevier
Associations between yogurt intake and risk of diet-related cardiometabolic diseases
(CMDs) have been the subject of recent research in epidemiologic nutrition. A healthy …

[HTML][HTML] Anti-diabetic effect by walnut (Juglans mandshurica Maxim.)-derived peptide LPLLR through inhibiting α-glucosidase and α-amylase, and alleviating insulin …

J Wang, T Wu, L Fang, C Liu, X Liu, H Li, J Shi… - Journal of Functional …, 2020 - Elsevier
In the present study, a novel pentapeptide LPLLR (Leu-Pro-Leu-Leu-Arg) was purified and
identified from walnut protein hydrolysates (3–10 kDa) by SEC, RP-HPLC, and LC-MS/MS …

Screening and identification of a novel antidiabetic peptide from collagen hydrolysates of Chinese giant salamander skin: network pharmacology, inhibition kinetics …

M Zhou, G Ren, B Zhang, F Ma, J Fan, Z Qiu - Food & Function, 2022 - pubs.rsc.org
In this study, a novel peptide GPPGPA was screened from the collagen hydrolysates of
Chinese giant salamander (Andrias davidianus) skin, and its anti-diabetes mechanism was …

Walnut-derived peptides promote autophagy via the activation of AMPK/mTOR/ULK1 pathway to ameliorate hyperglycemia in type 2 diabetic mice

W Hou, F Zhao, L Fang, X Wang, D Wu… - Journal of Agricultural …, 2023 - ACS Publications
Autophagy flux plays a significant protective role in type 2 diabetes mellitus (T2DM).
However, the mechanisms by which autophagy mediates insulin resistance (IR) to …

Glycomacropeptide bioactivity and health: a review highlighting action mechanisms and signaling pathways

LE Córdova-Dávalos, M Jiménez, E Salinas - Nutrients, 2019 - mdpi.com
Food-derived bioactive peptides are reported as beneficial and safe for human health.
Glycomacropeptide (GMP) is a milk-protein-derived peptide that, in addition to its nutritional …

[HTML][HTML] Identification of novel peptides from goat milk casein that ameliorate high-glucose-induced insulin resistance in HepG2 cells

H Gong, J Gao, Y Wang, QW Luo, KR Guo, FZ Ren… - Journal of Dairy …, 2020 - Elsevier
In this study, we investigated the effect of goat milk casein hydrolysates on glucose
consumption rate, intracellular glycogen concentration, and mRNA expression of …

A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling …

X Zhang, A Liu, Y Zhang, M Zhou, X Li, M Fu… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Alpinia officinarum Hance, a perennial natural
medicine-food herb, has been traditionally used to treat colds, stomachache, and diabetes …

Identification of cyanidin-3-arabinoside extracted from blueberry as a selective protein tyrosine phosphatase 1B inhibitor

JL Tian, XJ Liao, YH Wang, X Si, C Shu… - Journal of agricultural …, 2019 - ACS Publications
Protein tyrosine phosphatase 1B (PTP1B) is an important target for type 2 diabetes. PTP1B
inhibitors can reduce blood glucose levels by increasing insulin sensitivity. Anthocyanins …

[HTML][HTML] Protective effects of rutin on liver injury in type 2 diabetic db/db mice

W Liang, D Zhang, J Kang, X Meng, J Yang… - Biomedicine & …, 2018 - Elsevier
The aim of this study was to evaluate the protective effect of rutin on the liver of type 2
diabetic mice and explore the correlation mechanism. The db/db mice, selected as the type …