Human african trypanosomiasis

P Büscher, G Cecchi, V Jamonneau, G Priotto - The Lancet, 2017 - thelancet.com
Human African trypanosomiasis (sleeping sickness) is a parasitic infection that almost
invariably progresses to death unless treated. Human African trypanosomiasis caused …

The animal trypanosomiases and their chemotherapy: a review

F Giordani, LJ Morrison, TG Rowan, HP De Koning… - Parasitology, 2016 - cambridge.org
Pathogenic animal trypanosomes affecting livestock have represented a major constraint to
agricultural development in Africa for centuries, and their negative economic impact is …

Extracellular vesicles from Trypanosoma brucei mediate virulence factor transfer and cause host anemia

AJ Szempruch, SE Sykes, R Kieft, L Dennison… - Cell, 2016 - cell.com
Intercellular communication between parasites and with host cells provides mechanisms for
parasite development, immune evasion, and disease pathology. Bloodstream African …

An update on African trypanocide pharmaceutics and resistance

KI Kasozi, ET MacLeod, I Ntulume… - Frontiers in Veterinary …, 2022 - frontiersin.org
African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

Salivarian trypanosomosis: a review of parasites involved, their global distribution and their interaction with the innate and adaptive mammalian host immune system

M Radwanska, N Vereecke, V Deleeuw… - Frontiers in …, 2018 - frontiersin.org
Salivarian trypanosomes are single cell extracellular parasites that cause infections in a
wide range of hosts. Most pathogenic infections worldwide are caused by one of four major …

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): bluetongue

EFSA Panel on Animal Health and Welfare … - Efsa …, 2017 - Wiley Online Library
A specific concept of strain was developed in order to classify the BTV serotypes ever
reported in Europe based on their properties of animal health impact: the genotype …

Sending a message: extracellular vesicles of pathogenic protozoan parasites

AJ Szempruch, L Dennison, R Kieft… - Nature Reviews …, 2016 - nature.com
Parasitic unicellular eukaryotes use extracellular vesicles (EVs) as vehicles for intercellular
communication and host manipulation. By using various mechanisms to generate EVs and …

A Clinical and Epidemiological Investigation of the First Reported Human Infection With the Zoonotic Parasite Trypanosoma evansi in Southeast Asia

N Van Vinh Chau, L Buu Chau… - Clinical Infectious …, 2016 - academic.oup.com
Background. Trypanosoma is a genus of unicellular parasitic flagellate protozoa.
Trypanosoma brucei species and Trypanosoma cruzi are the major agents of human …

Zoonotic parasites of dromedary camels: so important, so ignored

A Sazmand, A Joachim, D Otranto - Parasites & vectors, 2019 - Springer
With a global population of about 35 million in 47 countries, dromedary camels play a crucial
role in the economy of many marginal, desert areas of the world where they survive under …

Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity

B Stijlemans, G Caljon, J Van Den Abbeele… - Frontiers in …, 2016 - frontiersin.org
The diseases caused by African trypanosomes (AT) are of both medical and veterinary
importance and have adversely influenced the economic development of sub-Saharan …