Thyroid and COVID-19: a review on pathophysiological, clinical and organizational aspects

G Lisco, A De Tullio, E Jirillo, VA Giagulli… - Journal of …, 2021 - Springer
Background Thyroid dysfunction has been observed in patients with COVID-19, and
endocrinologists are requested to understand this clinical issue. Pandemic-related …

Paradigms of dynamic control of thyroid hormone signaling

AC Bianco, A Dumitrescu, B Gereben… - Endocrine …, 2019 - academic.oup.com
Thyroid hormone (TH) molecules enter cells via membrane transporters and, depending on
the cell type, can be activated (ie, T4 to T3 conversion) or inactivated (ie, T3 to 3, 3′-diiodo-l …

The interplay of thyroid hormones and the immune system–where we stand and why we need to know about it

C Wenzek, A Boelen, AM Westendorf… - European journal of …, 2022 - academic.oup.com
Over the past few years, growing evidence suggests direct crosstalk between thyroid
hormones (THs) and the immune system. Components of the immune system were …

Thyroid hormone action on innate immunity

MM Montesinos, CG Pellizas - Frontiers in endocrinology, 2019 - frontiersin.org
The interplay between thyroid hormone action and the immune system has been
established in physiological and pathological settings. However, their connection is complex …

Modulating the function of the immune system by thyroid hormones and thyrotropin

EL Jara, N Muñoz-Durango, C Llanos, C Fardella… - Immunology letters, 2017 - Elsevier
Accumulating evidence suggests a close bidirectional communication and regulation
between the neuroendocrine and immune systems. Thyroid hormones (THs) can exert …

Liver macrophages and inflammation in physiology and physiopathology of non‐alcoholic fatty liver disease

R Thibaut, MC Gage, I Pineda‐Torra… - The FEBS …, 2022 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome, being a common comorbidity of type 2 diabetes and with important links to …

Nitric oxide generated by tumor-associated macrophages is responsible for cancer resistance to cisplatin and correlated with syntaxin 4 and acid sphingomyelinase …

C Perrotta, D Cervia, I Di Renzo, C Moscheni… - Frontiers in …, 2018 - frontiersin.org
Tumor microenvironment is fundamental for cancer progression and chemoresistance.
Among stromal cells tumor-associated macrophages (TAMs) represent the largest …

The effect of hyperthyroidism on cognitive function, neuroinflammation, and necroptosis in APP/PS1 mice

K Lou, S Liu, F Zhang, W Sun, X Su, W Bi, Q Yin… - Journal of Translational …, 2023 - Springer
Background Increasing evidence has linked the thyroid dysfunction to the pathogenesis of
dementia. Evidence from clinical studies has demonstrated that hypothyroidism is related to …

Role of macrophages in the endocrine system

A Rehman, P Pacher, G Haskó - Trends in Endocrinology & Metabolism, 2021 - cell.com
Macrophages are cells of the innate immune system that play myriad roles in the body.
Macrophages are known to reside in endocrine glands, and a body of evidence now …

Prospective role of thyroid disorders in monitoring COVID-19 pandemic

K Kumari, GBN Chainy, U Subudhi - Heliyon, 2020 - cell.com
COVID-19 pandemic has affected more than 200 countries and 1.3 million individuals have
deceased within eleven months. Intense research on COVID-19 occurrence and prevalence …