Polychlorinated biphenyls (PCBs) in the environment: occupational and exposure events, effects on human health and fertility

L Montano, C Pironti, G Pinto, M Ricciardi, A Buono… - Toxics, 2022 - mdpi.com
In the last decade or so, polychlorinated biphenyls (PCBs) garnered renewed attention in
the scientific community due to new evidence pointing at their continued presence in the …

[HTML][HTML] Advanced human developmental toxicity and teratogenicity assessment using human organoid models

M Li, J Gong, L Gao, T Zou, J Kang, H Xu - … and Environmental Safety, 2022 - Elsevier
Tremendous progress has been made in the field of toxicology leading to the advance of
developmental toxicity assessment. Conventional animal models and in vitro two …

[HTML][HTML] Early-life exposure to persistent organic pollutants (OCPs, PBDEs, PCBs, PFASs) and attention-deficit/hyperactivity disorder: A multi-pollutant analysis of a …

V Lenters, N Iszatt, J Forns, E Čechová, A Kočan… - Environment …, 2019 - Elsevier
Background Numerous ubiquitous environmental chemicals are established or suspected
neurotoxicants, and infants are exposed to a mixture of these during the critical period of …

Neurodevelopmental disorders and environmental toxicants: epigenetics as an underlying mechanism

NQV Tran, K Miyake - International journal of genomics, 2017 - Wiley Online Library
The increasing prevalence of neurodevelopmental disorders, especially autism spectrum
disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research …

Evidence implicating non-dioxin-like congeners as the key mediators of polychlorinated biphenyl (PCB) developmental neurotoxicity

C Klocke, PJ Lein - International journal of molecular sciences, 2020 - mdpi.com
Despite being banned from production for decades, polychlorinated biphenyls (PCBs)
continue to pose a significant risk to human health. This is due to not only the continued …

Levels and profiles of persistent organic pollutants in breast milk in China and their potential health risks to breastfed infants: A review

L Hu, D Luo, L Wang, M Yu, S Zhao, Y Wang… - Science of the Total …, 2021 - Elsevier
Although some persistent organic pollutants (POPs) were prohibited or limited in use several
decades ago, they are still frequently detected in the human body. The purpose of this study …

Cohort profile: the mother-child cohort in Crete, Greece (Rhea Study)

L Chatzi, V Leventakou, M Vafeiadi… - International journal …, 2017 - academic.oup.com
Epidemiological and animal research shows that disease aetiology often has to be
evaluated with a life course perspective, starting as close to the time of conception as …

A systematic review and meta-analysis of chemical exposures and attention-deficit/hyperactivity disorder in children

LV Dimitrov, JW Kaminski, JR Holbrook, RH Bitsko… - Prevention …, 2024 - Springer
Exposure to certain chemicals prenatally and in childhood can impact development and may
increase risk for attention-deficit/hyperactivity disorder (ADHD). Leveraging a larger set of …

[HTML][HTML] Endocrine disruptors also function as nervous disruptors and can be renamed endocrine and nervous disruptors (ENDs)

GE Seralini, G Jungers - Toxicology reports, 2021 - Elsevier
Endocrine disruption (ED) and endocrine disruptors (EDs) emerged as scientific concepts in
1995, after numerous chemical pollutants were found to be responsible for reproductive …

[HTML][HTML] Determinants of persistent organic pollutant (POP) concentrations in human breast milk of a cross-sectional sample of primiparous mothers in Belgium

R Aerts, I Van Overmeire, A Colles, M Andjelković… - Environment …, 2019 - Elsevier
Background Bio-accumulation of persistent organic pollutants (POPs) in the environment
and in the food chain can lead to high pollutant concentrations in human fat-containing …