High-throughput technologies are urgently needed for monitoring the formidable biodiversity
and functional capabilities of microorganisms in the environment. Ten years ago, DNA …

The increasing popularity of iTRAQ for quantitative proteomics applications makes it
necessary to evaluate its relevance, accuracy, and precision for biological interpretation …

DNA microarrays can be used for large number of application where high-throughput is
needed. The ability to probe a sample for hundred to million different molecules at once has …

In recent years, the development of fast and highly sensitive microscopy has changed the
way of thinking of cell biologists: it became more and more important to study the structural …

The close correlation between Tau pathology and Alzheimer's disease (AD) progression
makes this protein a suitable biomarker for diagnosis and monitoring of the disorder …

Plasmonic structures are known to affect the fluorescence properties of dyes placed in close
proximity. This effect has been exploited in combination with single-molecule techniques for …

DNA and protein microarrays are a high-throughput technology that allow the simultaneous
quantification of tens of thousands of different biomolecular species. The mediocre …

Determination of the sequence of the human genome and knowledge of the genetic code
have allowed rapid progress in the identification of mammalian proteins. However, far less is …

Background Pseudomonas aeruginosa is an opportunistic pathogen that is the major cause
of morbidity and mortality in patients with cystic fibrosis (CF). While most CF patients are …

We demonstrate that, contrary to current understanding, the density of probe molecules is
not responsible for the lack of hybridization in high density single-stranded DNA (ss-DNA) …