Bacterial virus forcing of bacterial O-antigen shields: lessons from Coliphages

AV Letarov - International Journal of Molecular Sciences, 2023 - mdpi.com
In most Gram-negative bacteria, outer membrane (OM) lipopolysaccharide (LPS) molecules
carry long polysaccharide chains known as the O antigens or O polysaccharides (OPS). The …

Cryo-electron microscopy in the study of virus entry and infection

M Dutta, P Acharya - Frontiers in Molecular Biosciences, 2024 - frontiersin.org
Viruses have been responsible for many epidemics and pandemics that have impacted
human life globally. The COVID-19 pandemic highlighted both our vulnerability to viral …

Cryo-EM analysis of Pseudomonas phage Pa193 structural components

SM Iglesias, CFD Hou, J Reid, E Schauer… - Communications …, 2024 - nature.com
Abstract The World Health Organization has designated Pseudomonas aeruginosa as a
critical pathogen for the development of new antimicrobials. Bacterial viruses, or …

About bacteriophage tail terminator and tail completion proteins: structure of the proximal extremity of siphophage T5 tail

R Linares, C Breyton - Journal of Virology, 2024 - journals.asm.org
Bacteriophages are viruses infecting bacteria. The vast majority of them bear a tail, allowing
host recognition, cell wall perforation, and DNA injection into the host cytoplasm. Using …

[HTML][HTML] Structures of Mature and Urea-Treated Empty Bacteriophage T5: Insights into Siphophage Infection and DNA Ejection

Y Peng, H Tang, H Xiao, W Chen, J Song… - International Journal of …, 2024 - mdpi.com
T5 is a siphophage that has been extensively studied by structural and biochemical
methods. However, the complete in situ structures of T5 before and after DNA ejection …

Cryo-EM structure of flagellotropic bacteriophage Chi

RR Sonani, NC Esteves, BE Scharf, EH Egelman - Structure, 2024 - cell.com
The flagellotropic bacteriophage χ (Chi) infects bacteria via the flagellar filament. Despite
years of study, its structural architecture remains partly characterized. Through cryo-EM, we …

[HTML][HTML] Cryo-EM analysis of Pseudomonas phage Pa193 structural components

G Cingolani, S Iglesias, CF Hou, S Lemire… - Research …, 2024 - ncbi.nlm.nih.gov
Abstract The World Health Organization has designated Pseudomonas aeruginosa as a
critical pathogen for the development of new antimicrobials. Bacterial viruses, or …

Structure of the Staphylococcus aureus bacteriophage 80a neck shows the interactions between DNA, tail completion protein and tape measure protein

JL Kizziah, A Mukherjee, LK Parker, T Dokland - bioRxiv, 2024 - biorxiv.org
Tailed bacteriophages with double-stranded DNA genomes (class Caudoviricetes) play an
important role in the evolution of bacterial pathogenicity, both as carriers of genes encoding …

High-Resolution Reconstruction of Entire Siphovirus

R Ayala, A Moiseenko, E Kulikov, A Letarov, M Wolf… - 2024 - academic.oup.com
Viruses are the most abundant and diverse biological entity on Earth. Specifically, within the
vast variety of viruses that can infect nearly all known forms of life, bacteriophages are the …