The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …

Nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the central
nervous system, being expressed in neurons and non-neuronal cells, where they participate …

Background α7 nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout
the central nervous system and are reported to have neuroprotective properties. α7 nAChRs …

Okadaic acid (OKA) is one of the main polyether toxins produced by marine microalgae
which causes diarrhetic shellfish poisoning. It is a selective and potent inhibitor of …

Accumulating evidence suggests that CNS α7 nicotinic acetylcholine receptors (nAChRs)
are important targets for the development of therapeutic approaches for Parkinson's disease …

In the central nervous system, deficits in cholinergic neurotransmission correlate with
decreased attention and cognitive impairment, while stimulation of neuronal nicotinic …

Alzheimer's disease (AD) is a neurodegenerative disease that is the leading cause of age-
related dementia. Currently, therapeutic agent delivery to the CNS is a valued approach for …

Aims: A loss in brain acetylcholine and cholinergic markers, subchronic inflammation, and
impaired mitochondrial function, which lead to low-energy production and high oxidative …

Neonicotinoids are one of most widely used pesticides targeting nicotinic acetylcholine
receptors (nAChRs) of insects. Recent epidemiological evidence revealed increasing …

Several evidences suggest that enhanced oxidative stress is involved in the pathogenesis
and/or progression of several neurodegenerative diseases. The aim of this study was to …