Staphylococcus aureus host interactions and adaptation

BP Howden, SG Giulieri, T Wong Fok Lung… - Nature Reviews …, 2023 - nature.com
Invasive Staphylococcus aureus infections are common, causing high mortality,
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …

Molecular and evolutionary determinants of bacteriophage host range

PA de Jonge, FL Nobrega, SJJ Brouns, BE Dutilh - Trends in microbiology, 2019 - cell.com
The host range of a bacteriophage is the taxonomic diversity of hosts it can successfully
infect. Host range, one of the central traits to understand in phages, is determined by a range …

Bacterial SNPs in the human gut microbiome associate with host BMI

L Zahavi, A Lavon, L Reicher, S Shoer, A Godneva… - Nature medicine, 2023 - nature.com
Genome-wide association studies (GWASs) have provided numerous associations between
human single-nucleotide polymorphisms (SNPs) and health traits. Likewise, metagenome …

Staphylococcus aureus in Animals

AF Haag, JR Fitzgerald, JR Penadés - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a mammalian commensal and opportunistic pathogen that
colonizes niches such as skin, nares and diverse mucosal membranes of about 20-30% of …

Population genomics of bacterial host adaptation

SK Sheppard, DS Guttman, JR Fitzgerald - Nature Reviews Genetics, 2018 - nature.com
Some bacteria can transfer to new host species, and this poses a risk to human health.
Indeed, an estimated 60% of all human pathogens have originated from other animal …

The evolutionary genomics of host specificity in Staphylococcus aureus

M Matuszewska, GGR Murray, EM Harrison… - Trends in …, 2020 - cell.com
Staphylococcus aureus is an important human bacterial pathogen that has a cosmopolitan
host range, including livestock, companion and wild animal species. Genomic and …

Genome degradation promotes Salmonella pathoadaptation by remodeling fimbriae-mediated proinflammatory response

X Zhou, X Kang, J Chen, Y Song, C Jia… - National Science …, 2023 - academic.oup.com
Understanding changes in pathogen behavior (eg increased virulence, a shift in
transmission channel) is critical for the public health management of emerging infectious …

Staphylococcus aureus in agriculture: lessons in evolution from a multispecies pathogen

S Park, J Ronholm - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Staphylococcus aureus is a formidable bacterial pathogen that is responsible for infections
in humans and various species of wild, companion, and agricultural animals. The ability of S …

Q&A: What are pathogens, and what have they done to and for us?

F Balloux, L van Dorp - BMC biology, 2017 - Springer
Microbes are found on us, within us and around us. They inhabit virtually every environment
on the planet and the bacteria carried by an average human, mostly in their gut, outnumber …

'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution

A McNally, NR Thomson, S Reuter… - Nature Reviews …, 2016 - nature.com
Pathogenic species in the Yersinia genus have historically been targets for research aimed
at understanding how bacteria evolve into mammalian pathogens. The advent of large-scale …