Sleep disturbances increase the risk of dementia: a systematic review and meta-analysis

L Shi, SJ Chen, MY Ma, YP Bao, Y Han, YM Wang… - Sleep medicine …, 2018 - Elsevier
Sleep disturbances and dementia are two common and significant health problems in older
adults. Investigations suggest that sleep disturbances might increase the risk of dementia …

Therapeutic potential of intermittent hypoxia: a matter of dose

A Navarrete-Opazo, GS Mitchell - American Journal of …, 2014 - journals.physiology.org
Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

Oxidative & nitrosative stress in depression: why so much stress?

S Moylan, M Berk, OM Dean, Y Samuni… - Neuroscience & …, 2014 - Elsevier
Many studies support a crucial role for oxidative & nitrosative stress (O&NS) in the
pathophysiology of unipolar and bipolar depression. These disorders are characterized inter …

Obstructive sleep apnoea syndrome

P Lévy, M Kohler, WT McNicholas, F Barbé… - Nature reviews Disease …, 2015 - nature.com
Obstructive sleep apnoea syndrome (OSAS) is a common clinical condition in which the
throat narrows or collapses repeatedly during sleep, causing obstructive sleep apnoea …

The ventilatory response to hypoxia in mammals: mechanisms, measurement, and analysis

LJ Teppema, A Dahan - Physiological reviews, 2010 - journals.physiology.org
The respiratory response to hypoxia in mammals develops from an inhibition of breathing
movements in utero into a sustained increase in ventilation in the adult. This ventilatory …

Obstructive sleep apnea and metabolic syndrome: alterations in glucose metabolism and inflammation

E Tasali, MSM Ip - Proceedings of the American Thoracic Society, 2008 - atsjournals.org
Metabolic syndrome (MS), the commonly used term for the clustering of obesity, insulin
resistance, hypertension, and dyslipidemia, affects millions of people worldwide, and is …

Hypoxia: the force that drives chronic kidney disease

Q Fu, SP Colgan, CS Shelley - Clinical medicine & research, 2016 - Marshfield Clinic
In the United States the prevalence of end-stage renal disease (ESRD) reached epidemic
proportions in 2012 with over 600,000 patients being treated. The rates of ESRD among the …

Memory and obstructive sleep apnea: a meta-analysis

A Wallace, RS Bucks - Sleep, 2013 - academic.oup.com
Abstract Study Objectives: To examine episodic memory performance in individuals with
obstructive sleep apnea (OSA). Design Meta-analysis was used to synthesize results from …

Intermittent hypoxia increases arterial blood pressure in humans through a renin-angiotensin system-dependent mechanism

GE Foster, PJ Hanly, SB Ahmed, AE Beaudin… - …, 2010 - Am Heart Assoc
Intermittent hypoxia (IH) is believed to contribute to the pathogenesis of hypertension in
obstructive sleep apnea through mechanisms that include activation of the renin-angiotensin …

Does obstructive sleep apnea cause endothelial dysfunction? A critical review of the literature

CM Hoyos, KL Melehan, PY Liu, RR Grunstein… - Sleep medicine …, 2015 - Elsevier
Endothelial dysfunction is characterized by impaired endothelium-dependent vasodilatation
and is an independent predictor of adverse cardiovascular consequences. The ease with …