The leishmaniases represent a public health problem in under-developed countries and are
considered a neglected disease by the World Health Organization (WHO). They are cuased …

There is no effective cure for Chagas disease, which is caused by infection with the
arthropod-borne parasite, Trypanosoma cruzi. In the search for new drugs to treat Chagas …

Leishmaniasis, a category 1 neglected protozoan disease caused by a kinetoplastid
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …

Intracellular human pathogens are the deadliest infectious diseases and pose great difficulty
to effectively treat due to their protection inside the host cell and the development of …

Leishmania donovani is the causative agent of visceral leishmaniasis. Annually, 500 million
new cases of infection are reported mainly in poor communities, decreasing the interest of …

In order to replicate, many parasites must invade host cells. Changes in the intracelhdar Ca
2ũ concentration ([Ca~-*]) of different parasites and tissue culttnv cells during their …

Leishmania is an intracellular protozoan parasite which causes Leishmaniasis, a global
health problem affecting millions of people throughout 89 different countries in the world …

Neglected tropical diseases represent a major sanitary problem and a huge economic
burden to endemic countries, and are currently expanding to non-endemic countries owing …

The need for novel and efficacious drugs against neglected parasitic diseases, such as
Leishmaniasis and American Trypanosomiasis, is certainly apparent. In this work, we …

Chagas disease (CD) is a neglected disease that is endemic to Central and South America
and is caused by the protozoan parasite Trypanosoma cruzi. The discovery of new drugs …